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Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats

This study presents a parametric analysis of the steady-state temperature elevation in rat skin models due to millimeter wave exposure at frequencies from 6–100 GHz. The statistical data of the thickness of skin layers, namely epidermis, dermis, dermal white adipose tissue, and panniculus carnosus,...

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Autores principales: Li, Kun, Hikage, Takashi, Masuda, Hiroshi, Ijima, Etsuko, Nagai, Akiko, Taguchi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575911/
https://www.ncbi.nlm.nih.gov/pubmed/37833400
http://dx.doi.org/10.1038/s41598-023-44572-y
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author Li, Kun
Hikage, Takashi
Masuda, Hiroshi
Ijima, Etsuko
Nagai, Akiko
Taguchi, Kenji
author_facet Li, Kun
Hikage, Takashi
Masuda, Hiroshi
Ijima, Etsuko
Nagai, Akiko
Taguchi, Kenji
author_sort Li, Kun
collection PubMed
description This study presents a parametric analysis of the steady-state temperature elevation in rat skin models due to millimeter wave exposure at frequencies from 6–100 GHz. The statistical data of the thickness of skin layers, namely epidermis, dermis, dermal white adipose tissue, and panniculus carnosus, were measured for the first time using the excised tissues of real male Sprague–Dawley rats. Based on the precise structure obtained from the histological analysis of rat skin, we solve the bioheat transfer equation to investigate the effects of changes in parameters, such as body parts and thermal constants, on the absorbed power density and temperature elevation of biological tissues. Owing to the notably thin dermal white adipose tissue layer, the surface temperature elevation in the rat head and dorsal skin at 6–100 GHz is 52.6–32.3% and 83.3–58.8% of the average values of different human skin models, respectively. Our results also reveal that the surface temperature elevation of rat skin may correlate with the tissue thickness and deep blood perfusion rates.
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spelling pubmed-105759112023-10-15 Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats Li, Kun Hikage, Takashi Masuda, Hiroshi Ijima, Etsuko Nagai, Akiko Taguchi, Kenji Sci Rep Article This study presents a parametric analysis of the steady-state temperature elevation in rat skin models due to millimeter wave exposure at frequencies from 6–100 GHz. The statistical data of the thickness of skin layers, namely epidermis, dermis, dermal white adipose tissue, and panniculus carnosus, were measured for the first time using the excised tissues of real male Sprague–Dawley rats. Based on the precise structure obtained from the histological analysis of rat skin, we solve the bioheat transfer equation to investigate the effects of changes in parameters, such as body parts and thermal constants, on the absorbed power density and temperature elevation of biological tissues. Owing to the notably thin dermal white adipose tissue layer, the surface temperature elevation in the rat head and dorsal skin at 6–100 GHz is 52.6–32.3% and 83.3–58.8% of the average values of different human skin models, respectively. Our results also reveal that the surface temperature elevation of rat skin may correlate with the tissue thickness and deep blood perfusion rates. Nature Publishing Group UK 2023-10-13 /pmc/articles/PMC10575911/ /pubmed/37833400 http://dx.doi.org/10.1038/s41598-023-44572-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Li, Kun
Hikage, Takashi
Masuda, Hiroshi
Ijima, Etsuko
Nagai, Akiko
Taguchi, Kenji
Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
title Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
title_full Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
title_fullStr Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
title_full_unstemmed Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
title_short Parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
title_sort parameter variation effects on millimeter wave dosimetry based on precise skin thickness in real rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575911/
https://www.ncbi.nlm.nih.gov/pubmed/37833400
http://dx.doi.org/10.1038/s41598-023-44572-y
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