Chromatin organization drives the search mechanism of nuclear factors

Nuclear factors rapidly scan the genome for their targets, but the role of nuclear organization in such search is uncharted. Here we analyzed how multiple factors explore chromatin, combining live-cell single-molecule tracking with multifocal structured illumination of DNA density. We find that fact...

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Detalles Bibliográficos
Autores principales: Mazzocca, Matteo, Loffreda, Alessia, Colombo, Emanuele, Fillot, Tom, Gnani, Daniela, Falletta, Paola, Monteleone, Emanuele, Capozi, Serena, Bertrand, Edouard, Legube, Gaelle, Lavagnino, Zeno, Tacchetti, Carlo, Mazza, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575952/
https://www.ncbi.nlm.nih.gov/pubmed/37833263
http://dx.doi.org/10.1038/s41467-023-42133-5

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