Structural basis of dimerization of chemokine receptors CCR5 and CXCR4

G protein-coupled receptors (GPCRs) are prominent drug targets responsible for extracellular-to-intracellular signal transduction. GPCRs can form functional dimers that have been poorly characterized so far. Here, we show the dimerization mechanism of the chemokine receptors CCR5 and CXCR4 by means...

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Detalles Bibliográficos
Autores principales: Di Marino, Daniele, Conflitti, Paolo, Motta, Stefano, Limongelli, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575954/
https://www.ncbi.nlm.nih.gov/pubmed/37833254
http://dx.doi.org/10.1038/s41467-023-42082-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575954/
https://www.ncbi.nlm.nih.gov/pubmed/37833254
http://dx.doi.org/10.1038/s41467-023-42082-z

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