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Structural basis of dimerization of chemokine receptors CCR5 and CXCR4
G protein-coupled receptors (GPCRs) are prominent drug targets responsible for extracellular-to-intracellular signal transduction. GPCRs can form functional dimers that have been poorly characterized so far. Here, we show the dimerization mechanism of the chemokine receptors CCR5 and CXCR4 by means...
Autores principales: | Di Marino, Daniele, Conflitti, Paolo, Motta, Stefano, Limongelli, Vittorio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575954/ https://www.ncbi.nlm.nih.gov/pubmed/37833254 http://dx.doi.org/10.1038/s41467-023-42082-z |
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