Synthetic viability induces resistance to immune checkpoint inhibitors in cancer cells

BACKGROUND: Immune checkpoint inhibitors (ICI) have revolutionized the treatment for multiple cancers. However, most of patients encounter resistance. Synthetic viability (SV) between genes could induce resistance. In this study, we established SV signature to predict the efficacy of ICI treatment f...

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Detalles Bibliográficos
Autores principales: Liu, Mingyue, Dong, Qi, Chen, Bo, Liu, Kaidong, Zhao, Zhangxiang, Wang, Yuquan, Zhuang, Shuping, Han, Huiming, Shi, Xingyang, Jin, Zixin, Hui, Yang, Gu, Yunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575993/
https://www.ncbi.nlm.nih.gov/pubmed/37620409
http://dx.doi.org/10.1038/s41416-023-02404-w

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