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Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk

BACKGROUND: Tobacco smoking is suggested as a risk factor for colorectal cancer (CRC), but the complex relationship and the potential pathway are not fully understood. METHODS: We performed two-sample Mendelian randomisation (MR) analyses with genetic instruments for smoking behaviours and related D...

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Detalles Bibliográficos
Autores principales:	Zhou, Xuan, Xiao, Qian, Jiang, Fangyuan, Sun, Jing, Wang, Lijuan, Yu, Lili, Zhou, Yajing, Zhao, Jianhui, Zhang, Han, Yuan, Shuai, Timofeeva, Maria, Spiliopoulou, Athina, Mesa-Eguiagaray, Ines, Farrington, Susan M., Law, Philip J., Houlston, Richard S., Ding, Kefeng, Dunlop, Malcolm G., Theodoratou, Evropi, Li, Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576058/ https://www.ncbi.nlm.nih.gov/pubmed/37608097 http://dx.doi.org/10.1038/s41416-023-02397-6

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