Histological diagnosis of polyploidy discriminates an aggressive subset of hepatocellular carcinomas with poor prognosis

BACKGROUND: Although genome duplication, or polyploidization, is believed to drive cancer evolution and affect tumor features, its significance in hepatocellular carcinoma (HCC) is unclear. We aimed to determine the characteristics of polyploid HCCs by evaluating chromosome duplication and to discov...

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Detalles Bibliográficos
Autores principales: Matsuura, Takanori, Ueda, Yoshihide, Harada, Yoshiyuki, Hayashi, Kazuki, Horisaka, Kisara, Yano, Yoshihiko, So, Shinichi, Kido, Masahiro, Fukumoto, Takumi, Kodama, Yuzo, Hara, Eiji, Matsumoto, Tomonori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576083/
https://www.ncbi.nlm.nih.gov/pubmed/37715023
http://dx.doi.org/10.1038/s41416-023-02408-6

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