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Endothelial discoidin domain receptor 1 senses flow to modulate YAP activation

Mechanotransduction in endothelial cells is critical to maintain vascular homeostasis and can contribute to disease development, yet the molecules responsible for sensing flow remain largely unknown. Here, we demonstrate that the discoidin domain receptor 1 (DDR1) tyrosine kinase is a direct mechano...

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Detalles Bibliográficos
Autores principales:	Liu, Jiayu, Zhao, Chuanrong, Xiao, Xue, Li, Aohan, Liu, Yueqi, Zhao, Jianan, Fan, Linwei, Liang, Zhenhui, Pang, Wei, Yao, Weijuan, Li, Wei, Zhou, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576099/ https://www.ncbi.nlm.nih.gov/pubmed/37833282 http://dx.doi.org/10.1038/s41467-023-42341-z

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