Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2/Akap12 signaling to preserve blood–brain barrier integrity

Neurobiological consequences of traumatic brain injury (TBI) result from a complex interplay of secondary injury responses and sequela that mediates chronic disability. Endothelial cells are important regulators of the cerebrovascular response to TBI. Our work demonstrates that genetic deletion of e...

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Detalles Bibliográficos
Autores principales: Cash, Alison, de Jager, Caroline, Brickler, Thomas, Soliman, Eman, Ladner, Liliana, Kaloss, Alexandra M., Zhu, Yumeng, Pridham, Kevin J., Mills, Jatia, Ju, Jing, Basso, Erwin Kristobal Gudenschwager, Chen, Michael, Johnson, Zachary, Sotiropoulos, Yianni, Wang, Xia, Xie, Hehuang, Matson, John B., Marvin, Eric A., Theus, Michelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576133/
https://www.ncbi.nlm.nih.gov/pubmed/37796990
http://dx.doi.org/10.1073/pnas.2204700120

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