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Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy
Narcolepsy is a sleep disorder caused by deficiency of orexin signaling. However, the neural mechanisms by which deficient orexin signaling causes the abnormal rapid eye movement (REM) sleep characteristics of narcolepsy, such as cataplexy and frequent transitions to REM states, are not fully unders...
Autores principales: | Ito, Hiroto, Fukatsu, Noriaki, Rahaman, Sheikh Mizanur, Mukai, Yasutaka, Izawa, Shuntaro, Ono, Daisuke, Kilduff, Thomas S., Yamanaka, Akihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576136/ https://www.ncbi.nlm.nih.gov/pubmed/37796986 http://dx.doi.org/10.1073/pnas.2301951120 |
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