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Effects of (−)‐MBP, a novel 5‐HT(2C) agonist and 5‐HT(2A/2B) antagonist/inverse agonist on brain activity: A phMRI study on awake mice

A novel serotonin ligand (−)‐MBP was developed for the treatment of schizophrenia that has 5‐HT(2A/2B) antagonist activity together with 5‐HT(2C) agonist activity. The multi‐functional activity of this novel drug candidate was characterized using pharmacological magnetic resonance imaging. It was hy...

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Detalles Bibliográficos
Autores principales: Sathe, Preeti K., Ramdasi, Gargi R., Giammatteo, Kaylie, Beauzile, Harvens, Wang, Shuyue, Zhang, Heng, Kulkarni, Praveen, Booth, Raymond G., Ferris, Craig F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576165/
https://www.ncbi.nlm.nih.gov/pubmed/37837184
http://dx.doi.org/10.1002/prp2.1144