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Effects of autologous serum on TREM2 and APOE in a personalized monocyte-derived macrophage assay of late-onset Alzheimer’s patients

BACKGROUND: Age-associated deterioration of the immune system contributes to a chronic low-grade inflammatory state known as “inflammaging” and is implicated in the pathogenesis of late-onset Alzheimer's disease (LOAD). Whether changes in the tissue environment caused by circulatory factors ass...

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Detalles Bibliográficos
Autores principales: Eren, Neriman, Gerike, Susanna, Üsekes, Berk, Peters, Oliver, Cosma, Nicoleta-Carmen, Hellmann-Regen, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576307/
https://www.ncbi.nlm.nih.gov/pubmed/37833781
http://dx.doi.org/10.1186/s12979-023-00376-2