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Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum

BACKGROUND: Low-grade, chronic inflammation in the central nervous system characterized by glial reactivity is one of the major hallmarks for aging-related neurodegenerative diseases like Alzheimer’s disease (AD). The basal forebrain cholinergic neurons (BFCN) provide the primary source of cholinerg...

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Detalles Bibliográficos
Autores principales: Gamage, Rashmi, Rossetti, Ilaria, Niedermayer, Garry, Münch, Gerald, Buskila, Yossi, Gyengesi, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576363/
https://www.ncbi.nlm.nih.gov/pubmed/37833764
http://dx.doi.org/10.1186/s12974-023-02897-5

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