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Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome

BACKGROUND: Raynaud’s syndrome (RS), also referred to as Raynaud’s phenomenon, is a vasospastic disorder causing episodic color changes in extremities upon exposure to cold or stress. These manifestations, either primary Raynaud’s phenomenon (PRP) or associated with connective tissue diseases like s...

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Autores principales: Yu, Fengwei, Liu, Yongtao, Zhang, Chengnian, Pang, Botao, Zhang, Daijie, Zhao, Wei, Li, Xuecheng, Yang, Weiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576400/
https://www.ncbi.nlm.nih.gov/pubmed/37838733
http://dx.doi.org/10.1186/s12893-023-02225-x
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author Yu, Fengwei
Liu, Yongtao
Zhang, Chengnian
Pang, Botao
Zhang, Daijie
Zhao, Wei
Li, Xuecheng
Yang, Weiqiang
author_facet Yu, Fengwei
Liu, Yongtao
Zhang, Chengnian
Pang, Botao
Zhang, Daijie
Zhao, Wei
Li, Xuecheng
Yang, Weiqiang
author_sort Yu, Fengwei
collection PubMed
description BACKGROUND: Raynaud’s syndrome (RS), also referred to as Raynaud’s phenomenon, is a vasospastic disorder causing episodic color changes in extremities upon exposure to cold or stress. These manifestations, either primary Raynaud’s phenomenon (PRP) or associated with connective tissue diseases like systemic sclerosis (SSc) as secondary Raynaud’s phenomenon (SRP), affect the quality of life. Current treatments range from calcium channel blockers to innovative surgical interventions, with evolving efficacy and safety profiles. METHODS: In this retrospective study, patients diagnosed with RS were selected based on complete medical records, ensuring homogeneity between groups. Surgeries involved microscopic excision of sympathetic nerve fibers and stripping of the digital artery’s adventitia. Postoperative care included antibiotics, analgesia, oral nifedipine, and heat therapies. Evaluation metrics such as the VAS pain score and RCS score were collected bi-weekly. Data analysis was conducted using SPSS 26.0, with significance set at p < 0.05. RESULTS: In total, 15 patients formed the experimental group, with five presenting fingertip soft tissue necrosis and ten showing RS symptoms. Comparative analysis of demographic data between experimental and control groups, both containing 15 participants, demonstrated no significant age and gender difference. However, the “Mean Duration of RP attack” in the experimental group was notably shorter (9.47 min ± 0.31) than the control group (19.33 min ± 1.79). The RS Severity Score also indicated milder severity for the experimental cohort (score: 8.55) compared to the control (score: 11.23). Postoperative assessments at 2, 4, and 6 weeks revealed improved VAS pain scores, RCS scores, and other measures for the experimental group, showing significant differences (p < 0.05). One distinctive case showcased a variation in the common digital nerve and artery course in an RS patient. CONCLUSION: Our retrospective analysis on RS patients indicates that microsurgical techniques are safe and effective in the short term. As surgical practices lean towards minimally invasive methods, our data supports this shift. However, extensive, prospective studies are essential for conclusive insights.
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spelling pubmed-105764002023-10-15 Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome Yu, Fengwei Liu, Yongtao Zhang, Chengnian Pang, Botao Zhang, Daijie Zhao, Wei Li, Xuecheng Yang, Weiqiang BMC Surg Research BACKGROUND: Raynaud’s syndrome (RS), also referred to as Raynaud’s phenomenon, is a vasospastic disorder causing episodic color changes in extremities upon exposure to cold or stress. These manifestations, either primary Raynaud’s phenomenon (PRP) or associated with connective tissue diseases like systemic sclerosis (SSc) as secondary Raynaud’s phenomenon (SRP), affect the quality of life. Current treatments range from calcium channel blockers to innovative surgical interventions, with evolving efficacy and safety profiles. METHODS: In this retrospective study, patients diagnosed with RS were selected based on complete medical records, ensuring homogeneity between groups. Surgeries involved microscopic excision of sympathetic nerve fibers and stripping of the digital artery’s adventitia. Postoperative care included antibiotics, analgesia, oral nifedipine, and heat therapies. Evaluation metrics such as the VAS pain score and RCS score were collected bi-weekly. Data analysis was conducted using SPSS 26.0, with significance set at p < 0.05. RESULTS: In total, 15 patients formed the experimental group, with five presenting fingertip soft tissue necrosis and ten showing RS symptoms. Comparative analysis of demographic data between experimental and control groups, both containing 15 participants, demonstrated no significant age and gender difference. However, the “Mean Duration of RP attack” in the experimental group was notably shorter (9.47 min ± 0.31) than the control group (19.33 min ± 1.79). The RS Severity Score also indicated milder severity for the experimental cohort (score: 8.55) compared to the control (score: 11.23). Postoperative assessments at 2, 4, and 6 weeks revealed improved VAS pain scores, RCS scores, and other measures for the experimental group, showing significant differences (p < 0.05). One distinctive case showcased a variation in the common digital nerve and artery course in an RS patient. CONCLUSION: Our retrospective analysis on RS patients indicates that microsurgical techniques are safe and effective in the short term. As surgical practices lean towards minimally invasive methods, our data supports this shift. However, extensive, prospective studies are essential for conclusive insights. BioMed Central 2023-10-14 /pmc/articles/PMC10576400/ /pubmed/37838733 http://dx.doi.org/10.1186/s12893-023-02225-x Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Yu, Fengwei
Liu, Yongtao
Zhang, Chengnian
Pang, Botao
Zhang, Daijie
Zhao, Wei
Li, Xuecheng
Yang, Weiqiang
Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome
title Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome
title_full Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome
title_fullStr Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome
title_full_unstemmed Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome
title_short Efficacy analysis of minimally invasive surgery for Raynaud’s syndrome
title_sort efficacy analysis of minimally invasive surgery for raynaud’s syndrome
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576400/
https://www.ncbi.nlm.nih.gov/pubmed/37838733
http://dx.doi.org/10.1186/s12893-023-02225-x
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