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A study on the preparation conditions of lidocaine microemulsion based on multi-objective genetic algorithm

Background: Topical lidocaine microemulsion preparations with low toxicity, low irritation, strong transdermal capability and convenient administration are urgently needed. Methods: Box-Behnken design was performed for three preparation conditions of 5% lidocaine microemulsions: mass ratio of the ma...

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Detalles Bibliográficos
Autores principales: Qiao, Yuchao, Wang, Xuchun, Ren, Hao, Cui, Yu, Ren, Jiahui, Hao, Chongqi, Zhao, Zhiyang, Liu, Jing, Zhao, Ruiqing, Li, Yiting, Tian, Qingping, Qiu, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576434/
https://www.ncbi.nlm.nih.gov/pubmed/37841920
http://dx.doi.org/10.3389/fphar.2023.1272454