Cullin‐associated and neddylation‐dissociated 1 regulate reprogramming of lipid metabolism through SKP1‐Cullin‐1‐F‐box(FBXO11)‐mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma

BACKGROUND: Enhanced de novo lipogenesis is essential for hepatocellular carcinoma (HCC). Abnormally high cullin‐associated and neddylation‐dissociated 1 (CAND1) expression is associated with poor clinical prognosis in HCC. The SKP1‐Cullin‐1‐F‐box (SCF) complex consists of the SKP1, Cullin‐1 and F‐b...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Xia, Peng, Yang, Zhangshuo, Liu, Jie, Zhu, Yimin, Huang, Zan, Zhang, Zhonglin, Yuan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576442/
https://www.ncbi.nlm.nih.gov/pubmed/37837399
http://dx.doi.org/10.1002/ctm2.1443

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