Cargando…

miR‐10b‐5p rescues leaky gut linked with gastrointestinal dysmotility and diabetes

BACKGROUND/AIM: Diabetes has substantive co‐occurrence with disorders of gut‐brain interactions (DGBIs). The pathophysiological and molecular mechanisms linking diabetes and DGBIs are unclear. MicroRNAs (miRNAs) are key regulators of diabetes and gut dysmotility. We investigated whether impaired gut...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zogg, Hannah, Singh, Rajan, Ha, Se Eun, Wang, Zhuqing, Jin, Byungchang, Ha, Mariah, Dafinone, Mirabel, Batalon, Tylar, Hoberg, Nicholas, Poudrier, Sandra, Nguyen, Linda, Yan, Wei, Layden, Brian T., Dugas, Lara R., Sanders, Kenton M., Ro, Seungil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Neurogastroenterology & Motility
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576606/ https://www.ncbi.nlm.nih.gov/pubmed/37723933 http://dx.doi.org/10.1002/ueg2.12463

Ejemplares similares

An organotypic slice model for ex vivo study of neural, immune, and microbial interactions of mouse intestine
por: Schwerdtfeger, Luke A., et al.
Publicado: (2015)

Electrophysiological characterization of human rectal afferents
por: Ng, Kheng-Seong, et al.
Publicado: (2016)

A pilot genome‐wide association study meta‐analysis of gastroparesis
por: Tavares, Leticia Camargo, et al.
Publicado: (2023)

Patients with symptoms of delayed gastric emptying have a high prevalence of oesophageal dysmotility, irrespective of scintigraphic evidence of gastroparesis
por: Triadafilopoulos, George, et al.
Publicado: (2017)

Current Treatment Options and Therapeutic Insights for Gastrointestinal Dysmotility and Functional Gastrointestinal Disorders
por: Singh, Rajan, et al.
Publicado: (2022)

Gut Microbial Dysbiosis in the Pathogenesis of Gastrointestinal Dysmotility and Metabolic Disorders
por: Singh, Rajan, et al.
Publicado: (2021)

Prior hospital‐based infection and risk of eosinophilic esophagitis in a Swedish nationwide case‐control study
por: Uchida, Amiko M., et al.
Publicado: (2022)

Pathophysiological mechanisms underlying gastrointestinal symptoms in patients with COVID-19
por: Jin, Byungchang, et al.
Publicado: (2021)

Persistent constipation and abdominal adverse events with newer treatments for constipation
por: Sonu, Irene, et al.
Publicado: (2016)

Incidence of ‘new-onset’ constipation and associated factors during lockdown due to the COVID-19 pandemic
por: Remes-Troche, Jose Maria, et al.
Publicado: (2021)

Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers
por: Ha, Se Eun, et al.
Publicado: (2022)

Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
por: Akbar, A, et al.
Publicado: (2008)

A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia
por: Matsueda, Kei, et al.
Publicado: (2011)

Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus
por: Tsuchida, Yasuaki, et al.
Publicado: (2010)

A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea
por: Garsed, Klara, et al.
Publicado: (2014)

Construction and validation of a questionnaire distinguishing a chronic abdominal wall pain syndrome from irritable bowel syndrome
por: van Assen, Tijmen, et al.
Publicado: (2012)

Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit
por: Tooth, David, et al.
Publicado: (2014)

Mechanisms of activation of mouse and human enteroendocrine cells by nutrients
por: Symonds, Erin L, et al.
Publicado: (2015)

Randomised controlled trial of mesalazine in IBS
por: Barbara, Giovanni, et al.
Publicado: (2016)

A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D)
por: Lam, Ching, et al.
Publicado: (2016)

Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1
por: Zhou, QiQi, et al.
Publicado: (2016)

Apelin targets gut contraction to control glucose metabolism via the brain
por: Fournel, Audren, et al.
Publicado: (2017)

Utility of high-resolution anorectal manometry and wireless motility capsule in the evaluation of patients with Parkinson's disease and chronic constipation
por: Su, Andrew, et al.
Publicado: (2016)

Ex vivo study of human visceral nociceptors
por: McGuire, Cian, et al.
Publicado: (2018)

Proof of concept: short-term non-invasive cervical vagus nerve stimulation in patients with drug-refractory gastroparesis
por: Paulon, Emma, et al.
Publicado: (2017)

Irf4-dependent CD103(+)CD11b(+) dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus
por: Pohl, Judith-Mira, et al.
Publicado: (2017)

Assessing telephone-delivered cognitive–behavioural therapy (CBT) and web-delivered CBT versus treatment as usual in irritable bowel syndrome (ACTIB): a multicentre randomised trial
por: Everitt, Hazel Anne, et al.
Publicado: (2019)

Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons
por: Stakenborg, Nathalie, et al.
Publicado: (2019)

Single-cell RNAseq reveals seven classes of colonic sensory neuron
por: Hockley, James R F, et al.
Publicado: (2019)

Changes in neuromuscular structure and functions of human colon during ageing are region-dependent
por: Broad, John, et al.
Publicado: (2019)

Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome
por: Henström, Maria, et al.
Publicado: (2018)

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA(B) receptors
por: Castro, Joel, et al.
Publicado: (2017)

miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea
por: Martínez, Cristina, et al.
Publicado: (2017)

Epithelial expression and function of trypsin-3 in irritable bowel syndrome
por: Rolland-Fourcade, Claire, et al.
Publicado: (2017)

microRNA overexpression in slow transit constipation leads to reduced Na(V)1.5 current and altered smooth muscle contractility
por: Mazzone, Amelia, et al.
Publicado: (2020)

Triage guidance for upper gastrointestinal physiology investigations during restoration of services during the COVID-19 pandemic
por: Sykes, Catherine, et al.
Publicado: (2020)

Serum L‐arginine and endogenous methylarginine concentrations predict irritable bowel syndrome in adults: A nested case‐control study
por: McEvoy, Mark A., et al.
Publicado: (2021)

Effectiveness of PPI treatment and guideline adherence in 236 patients with eosinophilic oesophagitis—Results from the population‐based DanEoE cohort shows a low complication rate
por: Frandsen, Line Tegtmeier, et al.
Publicado: (2021)

Coeliac disease enteropathy and symptoms may be aggravated by angiotensin receptor blockers in patients on a gluten‐free diet
por: O'Morain, Neil, et al.
Publicado: (2021)

A trial‐based economic evaluation of peppermint oil for the treatment of irritable bowel syndrome
por: Weerts, Zsa Zsa R. M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ubp0iu4afpmb7l60ojelttq1gh