Cargando…

Combined measure of salivary alpha-synuclein species as diagnostic biomarker for Parkinson’s disease

Parkinson’s disease (PD) diagnosis is still vulnerable to bias, and a definitive diagnosis often relies on post-mortem neuropathological diagnosis. In this regard, alpha-synuclein (αsyn)-specific in vivo biomarkers remain a critical unmet need, based on its relevance in the neuropathology. Specifica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Angius, Fabrizio, Mocci, Ignazia, Ercoli, Tommaso, Loy, Francesco, Fadda, Laura, Palmas, Maria Francesca, Cannas, Giada, Manzin, Aldo, Defazio, Giovanni, Carta, Anna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Short Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576686/ https://www.ncbi.nlm.nih.gov/pubmed/37552278 http://dx.doi.org/10.1007/s00415-023-11893-x

Ejemplares similares

Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers
por: Boi, Laura, et al.
Publicado: (2020)

Frequency and Determinants of Olfactory Hallucinations in Parkinson’s Disease Patients
por: Solla, Paolo, et al.
Publicado: (2021)

Olfactory Impairment in Parkinson’s Disease Patients with Tremor Dominant Subtype Compared to Those with Akinetic Rigid Dominant Subtype: A Pilot Study
por: Solla, Paolo, et al.
Publicado: (2022)

α-Synuclein seeding activity in duodenum biopsies from Parkinson’s disease patients
por: Vascellari, Sarah, et al.
Publicado: (2023)

Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson’s Disease
por: Vivacqua, Giorgio, et al.
Publicado: (2016)

Alpha-synuclein–mediated DNA damage, STING activation, and neuroinflammation in Parkinson’s disease
por: Standaert, David G., et al.
Publicado: (2022)

Olfactory Impairment Correlates with Executive Functions Disorders and Other Specific Cognitive Dysfunctions in Parkinson’s Disease
por: Solla, Paolo, et al.
Publicado: (2023)

SARS-CoV-2 and Its Variants: The Pandemic of Unvaccinated
por: Angius, Fabrizio, et al.
Publicado: (2021)

Lighting Up Alpha-synuclein Oligomers
por: Richter, Franziska
Publicado: (2018)

Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease
por: Meloni, Mario, et al.
Publicado: (2021)

Rasagiline Withdrawal Syndrome in Parkinson’s Disease
por: Solla, Paolo, et al.
Publicado: (2022)

Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson’s Disease
por: Palmas, Maria Francesca, et al.
Publicado: (2022)

Chemical disaggregation of alpha-synuclein fibrils as a therapy for synucleinopathies
por: Wu, Shenjie, et al.
Publicado: (2023)

Transmission of alpha-synuclein in Parkinson’s disease
por: Lee, Virginia M-Y
Publicado: (2013)

Alpha-synuclein spreading in Parkinson’s disease
por: Recasens, Ariadna, et al.
Publicado: (2014)

Alpha-Synuclein Aggregation in Parkinson's Disease
por: Srinivasan, E., et al.
Publicado: (2021)

Effect of Olfactory and Gustatory Dysfunction and Motor Symptoms on Body Weight in Patients with Parkinson’s Disease
por: Masala, Carla, et al.
Publicado: (2020)

Salivary alpha‐synuclein as a potential fluid biomarker in Parkinson’s disease: A systematic review and meta‐analysis
por: Kharel, Sanjeev, et al.
Publicado: (2022)

Modeling Parkinson’s Disease With the Alpha-Synuclein Protein
por: Gómez-Benito, Mónica, et al.
Publicado: (2020)

Alpha-Synuclein and Cognitive Decline in Parkinson Disease
por: Fan, Tian-Sin, et al.
Publicado: (2021)

Cerebrospinal Fluid Lysosomal Enzymes and Alpha-Synuclein in Parkinson's Disease
por: Parnetti, Lucilla, et al.
Publicado: (2014)

Salivary total α-synuclein, oligomeric α-synuclein and SNCA variants in Parkinson’s disease patients
por: Kang, Wenyan, et al.
Publicado: (2016)

The Convergence of Dopamine and α-Synuclein: Implications for Parkinson’s Disease
por: Mor, Danielle E, et al.
Publicado: (2018)

Neuroprotection by the Immunomodulatory Drug Pomalidomide in the Drosophila LRRK2(WD40) Genetic Model of Parkinson’s Disease
por: Casu, Maria Antonietta, et al.
Publicado: (2020)

Rationale for Therapeutic Silencing of Alpha-Synuclein in Parkinson’s Disease
por: Maraganore, Demetrius M.
Publicado: (2011)

Interaction between Neuromelanin and Alpha-Synuclein in Parkinson’s Disease
por: Xu, Shengli, et al.
Publicado: (2015)

Immunotherapy in Parkinson’s Disease: Micromanaging Alpha-Synuclein Aggregation
por: George, Sonia, et al.
Publicado: (2015)

New Perspectives on Roles of Alpha-Synuclein in Parkinson’s Disease
por: Zhang, Guoxin, et al.
Publicado: (2018)

The Identification of Alpha-Synuclein as the First Parkinson Disease Gene
por: Nussbaum, Robert L.
Publicado: (2017)

Alpha-Synuclein Pathology and the Role of the Microbiota in Parkinson’s Disease
por: Fitzgerald, Emily, et al.
Publicado: (2019)

Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease
por: Fields, Carroll Rutherford, et al.
Publicado: (2019)

Editorial: Biomarkers and Pathogenesis of Alpha-Synuclein in Parkinson's Disease
por: Li, Puyu, et al.
Publicado: (2021)

Parkinson’s Disease: A Prionopathy?
por: Vascellari, Sarah, et al.
Publicado: (2021)

Temperature-Dependent Structural Changes of Parkinson's Alpha-Synuclein Reveal the Role of Pre-Existing Oligomers in Alpha-Synuclein Fibrillization
por: Ariesandi, Winny, et al.
Publicado: (2013)

Olfactory Deficits in an Alpha-Synuclein Fly Model of Parkinson’s Disease
por: Chen, Alex Y., et al.
Publicado: (2014)

Gastrointestinal Biopsies for the Diagnosis of Alpha-Synuclein Pathology in Parkinson's Disease
por: Cersosimo, Maria Graciela
Publicado: (2015)

Microglia Response During Parkinson’s Disease: Alpha-Synuclein Intervention
por: Ferreira, Sara A., et al.
Publicado: (2018)

Alpha-synuclein, Proteotoxicity and Parkinson's Disease: Search for Neuroprotective Therapy
por: Ganguly, Upasana, et al.
Publicado: (2018)

Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism
por: Limanaqi, Fiona, et al.
Publicado: (2019)

Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles
por: Meade, Richard M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5uh1ilsstc87qif238ka8htkuk