HLA-B*44 and the Bw4-80T motif are associated with poor outcome of relapse-preventive immunotherapy in acute myeloid leukemia

HLA-B alleles are associated with outcomes in various pathologies, including autoimmune diseases and malignancies. The encoded HLA-B proteins are pivotal in antigen presentation to cytotoxic T cells, and some variants containing a Bw4 motif also serve as ligands to the killer immunoglobulin-like rec...

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Detalles Bibliográficos
Autores principales: Komic, Hana, Hallner, Alexander, Hussein, Brwa Ali, Badami, Chiara, Wöhr, Anne, Hellstrand, Kristoffer, Bernson, Elin, Thorén, Fredrik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576699/
https://www.ncbi.nlm.nih.gov/pubmed/37597015
http://dx.doi.org/10.1007/s00262-023-03506-3

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