PD-L1-expressing cancer-associated fibroblasts induce tumor immunosuppression and contribute to poor clinical outcome in esophageal cancer

The programmed cell death 1 protein (PD-1)/programmed cell death ligand 1 (PD-L1) axis plays a crucial role in tumor immunosuppression, while the cancer-associated fibroblasts (CAFs) have various tumor-promoting functions. To determine the advantage of immunotherapy, the relationship between the can...

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Detalles Bibliográficos
Autores principales: Kawasaki, Kento, Noma, Kazuhiro, Kato, Takuya, Ohara, Toshiaki, Tanabe, Shunsuke, Takeda, Yasushige, Matsumoto, Hijiri, Nishimura, Seitaro, Kunitomo, Tomoyoshi, Akai, Masaaki, Kobayashi, Teruki, Nishiwaki, Noriyuki, Kashima, Hajime, Maeda, Naoaki, Kikuchi, Satoru, Tazawa, Hiroshi, Shirakawa, Yasuhiro, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576702/
https://www.ncbi.nlm.nih.gov/pubmed/37668710
http://dx.doi.org/10.1007/s00262-023-03531-2

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