Systematic vitamin D supplementation is associated with improved outcomes and reduced thyroid adverse events in patients with cancer treated with immune checkpoint inhibitors: results from the prospective PROVIDENCE study

BACKGROUND: Hypovitaminosis D can have a negative prognostic impact in patients with cancer. Vitamin D has a demonstrated role in T-cell-mediated immune activation. We hypothesized that systematic vitamin D repletion could impact clinical outcomes in patients with cancer receiving immune-checkpoint...

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Detalles Bibliográficos
Autores principales: Bersanelli, Melissa, Cortellini, Alessio, Leonetti, Alessandro, Parisi, Alessandro, Tiseo, Marcello, Bordi, Paola, Michiara, Maria, Bui, Simona, Cosenza, Agnese, Ferri, Leonarda, Giudice, Giulia Claire, Testi, Irene, Rapacchi, Elena, Camisa, Roberta, Vincenzi, Bruno, Caruso, Giuseppe, Rauti, Antonio Natale, Arturi, Federica, Tucci, Marco, Santo, Valentina, Ricozzi, Valentina, Burtet, Vanessa, Sgargi, Paolo, Todeschini, Renata, Zustovich, Fable, Stucci, Luigia Stefania, Santini, Daniele, Buti, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576732/
https://www.ncbi.nlm.nih.gov/pubmed/37638980
http://dx.doi.org/10.1007/s00262-023-03522-3

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