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Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) responds poorly to systemic treatment, including new immunotherapeutic approaches. Biomarkers are urgently needed for early disease detection, patient stratification for treatment, and response prediction. The role of soluble CD40 (sCD40) is unknown in PDAC. I...

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Detalles Bibliográficos
Autores principales: Digomann, David, Heiduk, Max, Reiche, Charlotte, Glück, Jessica, Kahlert, Christoph, Mirtschink, Peter, Klimova, Anna, Bösch, Florian, Tonn, Torsten, Gaedcke, Jochen, Ghadimi, Michael, Weitz, Jürgen, Seifert, Lena, Seifert, Adrian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576756/
https://www.ncbi.nlm.nih.gov/pubmed/37838778
http://dx.doi.org/10.1038/s41698-023-00459-9

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