A robust yeast biocontainment system with two-layered regulation switch dependent on unnatural amino acid

Synthetic auxotrophy in which cell viability depends on the presence of an unnatural amino acid (unAA) provides a powerful strategy to restrict unwanted propagation of genetically modified organisms (GMOs) in open environments and potentially prevent industrial espionage. Here, we describe a generic...

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Detalles Bibliográficos
Autores principales: Chang, Tiantian, Ding, Weichao, Yan, Shirui, Wang, Yun, Zhang, Haoling, Zhang, Yu, Ping, Zhi, Zhang, Huiming, Huang, Yijian, Zhang, Jiahui, Wang, Dan, Zhang, Wenwei, Xu, Xun, Shen, Yue, Fu, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576815/
https://www.ncbi.nlm.nih.gov/pubmed/37838746
http://dx.doi.org/10.1038/s41467-023-42358-4

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