AMPK activation protects against prostate cancer by inducing a catabolic cellular state

Emerging evidence indicates that metabolic dysregulation drives prostate cancer (PCa) progression and metastasis. AMP-activated protein kinase (AMPK) is a master regulator of metabolism, although its role in PCa remains unclear. Here, we show that genetic and pharmacological activation of AMPK provi...

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Detalles Bibliográficos
Autores principales: Penfold, Lucy, Woods, Angela, Pollard, Alice E., Arizanova, Julia, Pascual-Navarro, Eneko, Muckett, Phillip J., Dore, Marian H., Montoya, Alex, Whilding, Chad, Fets, Louise, Mokochinski, Joao, Constantin, Theodora A., Varela-Carver, Anabel, Leach, Damien A., Bevan, Charlotte L., Nikitin, Alexander Yu., Hall, Zoe, Carling, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576838/
https://www.ncbi.nlm.nih.gov/pubmed/37061917
http://dx.doi.org/10.1016/j.celrep.2023.112396

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