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Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report

The incidence of gastrointestinal metastases from breast cancer (BC) is low. We report a special case of Luminal B (Hormone Receptor positive [HR+]/Human Epidermal Growth Factor receptor 2-positive [HER-2+]) BC. The patient presented with asymptomatic brain metastases two years after radical surgery...

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Autores principales: Yang, Si-Yuan, Zhang, Ji, Yang, Zhuang-Qing, Duan, Jia-Jun, Zhang, Ying, Li, Ming-Ke, Wang, Lei, Ye, Chun-mei, Nie, Jian-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576924/
https://www.ncbi.nlm.nih.gov/pubmed/37828835
http://dx.doi.org/10.1177/00368504231201043
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author Yang, Si-Yuan
Zhang, Ji
Yang, Zhuang-Qing
Duan, Jia-Jun
Zhang, Ying
Li, Ming-Ke
Wang, Lei
Ye, Chun-mei
Nie, Jian-Yun
author_facet Yang, Si-Yuan
Zhang, Ji
Yang, Zhuang-Qing
Duan, Jia-Jun
Zhang, Ying
Li, Ming-Ke
Wang, Lei
Ye, Chun-mei
Nie, Jian-Yun
author_sort Yang, Si-Yuan
collection PubMed
description The incidence of gastrointestinal metastases from breast cancer (BC) is low. We report a special case of Luminal B (Hormone Receptor positive [HR+]/Human Epidermal Growth Factor receptor 2-positive [HER-2+]) BC. The patient presented with asymptomatic brain metastases two years after radical surgery for modified breast cancer and developed right lower abdominal pain during relief therapy. Electronic gastroenteroscopy revealed inflammatory changes in the cecal mucosa. These changes were confirmed on pathology to be cecal metastasis from BC. The patient's condition was stabilised after treatment with an antibody-drug conjugate (ADC). For patients with BC who develop appendicitis-like symptoms after treatment for invasive ductal carcinoma of the breast, clinicians should be fully aware that the possibility of cecal metastasis needs to be considered, despite the very low probability of occurrence.
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spelling pubmed-105769242023-10-16 Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report Yang, Si-Yuan Zhang, Ji Yang, Zhuang-Qing Duan, Jia-Jun Zhang, Ying Li, Ming-Ke Wang, Lei Ye, Chun-mei Nie, Jian-Yun Sci Prog Medicine & Health Sciences The incidence of gastrointestinal metastases from breast cancer (BC) is low. We report a special case of Luminal B (Hormone Receptor positive [HR+]/Human Epidermal Growth Factor receptor 2-positive [HER-2+]) BC. The patient presented with asymptomatic brain metastases two years after radical surgery for modified breast cancer and developed right lower abdominal pain during relief therapy. Electronic gastroenteroscopy revealed inflammatory changes in the cecal mucosa. These changes were confirmed on pathology to be cecal metastasis from BC. The patient's condition was stabilised after treatment with an antibody-drug conjugate (ADC). For patients with BC who develop appendicitis-like symptoms after treatment for invasive ductal carcinoma of the breast, clinicians should be fully aware that the possibility of cecal metastasis needs to be considered, despite the very low probability of occurrence. SAGE Publications 2023-10-13 /pmc/articles/PMC10576924/ /pubmed/37828835 http://dx.doi.org/10.1177/00368504231201043 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Medicine & Health Sciences
Yang, Si-Yuan
Zhang, Ji
Yang, Zhuang-Qing
Duan, Jia-Jun
Zhang, Ying
Li, Ming-Ke
Wang, Lei
Ye, Chun-mei
Nie, Jian-Yun
Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report
title Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report
title_full Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report
title_fullStr Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report
title_full_unstemmed Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report
title_short Advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: A case report
title_sort advanced hormone receptor-positive/human epidermal growth factor receptor 2-positive invasive ductal carcinoma with cecal metastasis: a case report
topic Medicine & Health Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576924/
https://www.ncbi.nlm.nih.gov/pubmed/37828835
http://dx.doi.org/10.1177/00368504231201043
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