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Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience

Background/aim: Surgical repair techniques and management of patients with atrioventricular septal defect (AVSD) have progressed over the last few decades. Early and definitive interventions have become the choice of treatment for these patients. Based on this background, we aimed to review the earl...

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Autores principales: Kumar, Rupesh, Halder, Vikram, Ghosh, Soumitra, Thingnam, Shyam, Singh, Harkant, Mishra, Anand K, Mahajan, Sachin, Aggarwal, Pankaj, Dutta, Aduri Raja S, Mishra, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576971/
https://www.ncbi.nlm.nih.gov/pubmed/37846269
http://dx.doi.org/10.7759/cureus.45304
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author Kumar, Rupesh
Halder, Vikram
Ghosh, Soumitra
Thingnam, Shyam
Singh, Harkant
Mishra, Anand K
Mahajan, Sachin
Aggarwal, Pankaj
Dutta, Aduri Raja S
Mishra, Amit
author_facet Kumar, Rupesh
Halder, Vikram
Ghosh, Soumitra
Thingnam, Shyam
Singh, Harkant
Mishra, Anand K
Mahajan, Sachin
Aggarwal, Pankaj
Dutta, Aduri Raja S
Mishra, Amit
author_sort Kumar, Rupesh
collection PubMed
description Background/aim: Surgical repair techniques and management of patients with atrioventricular septal defect (AVSD) have progressed over the last few decades. Early and definitive interventions have become the choice of treatment for these patients. Based on this background, we aimed to review the early and mid-term outcomes of primary AVSD repair. Methods: A total of 53 patients with a mean age of 3.45 ± 5.67 years underwent definitive repair for AVSD between January 2014 and June 2021. The clinical data including age, type of defect, associated co-anomalies, symptoms, pulmonary hypertension, etc. were collected and assessed retrospectively. Mitral regurgitation (MR) as a clinical outcome was assessed at 0, 1, 2, and 5 years. Results: Among the recruited patients, 35 (66.1%) were male and 18 (33.9%) were female. Of 53 patients, repair for the complete defect was done in 38 (71.69%) patients, repair for intermediate/partial defect was done in 15 (23.1%) patients, and one patient underwent repair for incomplete type. Other associated co-anomalies were anterior mitral leaflet (12 (22.6%)), atrial and ventricular septal defect (VSD) (30 (56.6%)), and patent ductus arteriosus (PDA) (11 (20.8%)). Different procedures for surgical repair included patch closure, cleft repair, and polytetrafluoroethylene (PTFE) VSD closure. After repair, the mean follow-up period was 46.73 ± 27.37 months. Overall mortality was 3.78% (2/53), and two patients underwent reintervention due to symptomatic severe MR. Conclusions: A definitive and timely correction of AVSD shows satisfactory early and mid-term results.
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spelling pubmed-105769712023-10-16 Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience Kumar, Rupesh Halder, Vikram Ghosh, Soumitra Thingnam, Shyam Singh, Harkant Mishra, Anand K Mahajan, Sachin Aggarwal, Pankaj Dutta, Aduri Raja S Mishra, Amit Cureus Cardiac/Thoracic/Vascular Surgery Background/aim: Surgical repair techniques and management of patients with atrioventricular septal defect (AVSD) have progressed over the last few decades. Early and definitive interventions have become the choice of treatment for these patients. Based on this background, we aimed to review the early and mid-term outcomes of primary AVSD repair. Methods: A total of 53 patients with a mean age of 3.45 ± 5.67 years underwent definitive repair for AVSD between January 2014 and June 2021. The clinical data including age, type of defect, associated co-anomalies, symptoms, pulmonary hypertension, etc. were collected and assessed retrospectively. Mitral regurgitation (MR) as a clinical outcome was assessed at 0, 1, 2, and 5 years. Results: Among the recruited patients, 35 (66.1%) were male and 18 (33.9%) were female. Of 53 patients, repair for the complete defect was done in 38 (71.69%) patients, repair for intermediate/partial defect was done in 15 (23.1%) patients, and one patient underwent repair for incomplete type. Other associated co-anomalies were anterior mitral leaflet (12 (22.6%)), atrial and ventricular septal defect (VSD) (30 (56.6%)), and patent ductus arteriosus (PDA) (11 (20.8%)). Different procedures for surgical repair included patch closure, cleft repair, and polytetrafluoroethylene (PTFE) VSD closure. After repair, the mean follow-up period was 46.73 ± 27.37 months. Overall mortality was 3.78% (2/53), and two patients underwent reintervention due to symptomatic severe MR. Conclusions: A definitive and timely correction of AVSD shows satisfactory early and mid-term results. Cureus 2023-09-15 /pmc/articles/PMC10576971/ /pubmed/37846269 http://dx.doi.org/10.7759/cureus.45304 Text en Copyright © 2023, Kumar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Kumar, Rupesh
Halder, Vikram
Ghosh, Soumitra
Thingnam, Shyam
Singh, Harkant
Mishra, Anand K
Mahajan, Sachin
Aggarwal, Pankaj
Dutta, Aduri Raja S
Mishra, Amit
Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience
title Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience
title_full Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience
title_fullStr Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience
title_full_unstemmed Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience
title_short Early and Mid-Term Outcomes of Primary Repair After Atrioventricular Canal Defect: A Single-Center Eight-Year Experience
title_sort early and mid-term outcomes of primary repair after atrioventricular canal defect: a single-center eight-year experience
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576971/
https://www.ncbi.nlm.nih.gov/pubmed/37846269
http://dx.doi.org/10.7759/cureus.45304
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