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The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells
Emphysema and chronic obstructive pulmonary disease (COPD) most commonly result from the effects of environmental exposures in genetically susceptible individuals. Genome-wide association studies have implicated ADGRG6 in COPD and reduced lung function, and a limited number of studies have examined...
Autores principales: | Werder, Rhiannon B., Berthiaume, Kayleigh A., Merritt, Carly, Gallagher, Marissa, Villacorta-Martin, Carlos, Wang, Feiya, Bawa, Pushpinder, Malik, Vidhi, Lyons, Shawn M., Basil, Maria C., Morrisey, Edward E., Kotton, Darrell N., Zhou, Xiaobo, Cho, Michael H., Wilson, Andrew A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577075/ https://www.ncbi.nlm.nih.gov/pubmed/37734371 http://dx.doi.org/10.1016/j.ajhg.2023.08.017 |
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