Cargando…

Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid

It is presented here as a simple, selective, rapid, low-cost, with a wide linear range method to simultaneously determine tyrosine and uric acid using a modified carbon paste electrode decorated with graphene oxide and gold nanoparticles (GO/AuNPs/MCPE). In order to characterize and evaluate the mor...

Descripción completa

Detalles Bibliográficos
Autores principales: Garazhian, Elahe, Kalate Bojdi, Majid, Behbahani, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577133/
https://www.ncbi.nlm.nih.gov/pubmed/37840042
http://dx.doi.org/10.1038/s41598-023-44540-6
_version_ 1785121258603544576
author Garazhian, Elahe
Kalate Bojdi, Majid
Behbahani, Mohammad
author_facet Garazhian, Elahe
Kalate Bojdi, Majid
Behbahani, Mohammad
author_sort Garazhian, Elahe
collection PubMed
description It is presented here as a simple, selective, rapid, low-cost, with a wide linear range method to simultaneously determine tyrosine and uric acid using a modified carbon paste electrode decorated with graphene oxide and gold nanoparticles (GO/AuNPs/MCPE). In order to characterize and evaluate the morphology and constituents of the nanostructures, X-ray diffraction spectroscopy, Transmission electron microscopes, Dynamic light scattering, Zeta potential, electrochemical impedance spectroscopy, and Voltammetry were employed. The current response on the surface of the modified electrode had a dynamic linear range relationship in the concentrations of 0.14–340.00 µmol L(−1) and 0.06–141.00 µmol L(−1) for tyrosine and uric acid, respectively, and the method detection limit (MDL) was 0.0060 µmol L(−1) and 0.0037 µmol L(−1), respectively. This modified electrode provided high stability, sensitivity, and acceptable reproducibility for voltammetric measurements of tyrosine and uric acid simultaneously in a biological matrix.
format Online
Article
Text
id pubmed-10577133
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-105771332023-10-17 Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid Garazhian, Elahe Kalate Bojdi, Majid Behbahani, Mohammad Sci Rep Article It is presented here as a simple, selective, rapid, low-cost, with a wide linear range method to simultaneously determine tyrosine and uric acid using a modified carbon paste electrode decorated with graphene oxide and gold nanoparticles (GO/AuNPs/MCPE). In order to characterize and evaluate the morphology and constituents of the nanostructures, X-ray diffraction spectroscopy, Transmission electron microscopes, Dynamic light scattering, Zeta potential, electrochemical impedance spectroscopy, and Voltammetry were employed. The current response on the surface of the modified electrode had a dynamic linear range relationship in the concentrations of 0.14–340.00 µmol L(−1) and 0.06–141.00 µmol L(−1) for tyrosine and uric acid, respectively, and the method detection limit (MDL) was 0.0060 µmol L(−1) and 0.0037 µmol L(−1), respectively. This modified electrode provided high stability, sensitivity, and acceptable reproducibility for voltammetric measurements of tyrosine and uric acid simultaneously in a biological matrix. Nature Publishing Group UK 2023-10-15 /pmc/articles/PMC10577133/ /pubmed/37840042 http://dx.doi.org/10.1038/s41598-023-44540-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Garazhian, Elahe
Kalate Bojdi, Majid
Behbahani, Mohammad
Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
title Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
title_full Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
title_fullStr Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
title_full_unstemmed Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
title_short Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
title_sort decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577133/
https://www.ncbi.nlm.nih.gov/pubmed/37840042
http://dx.doi.org/10.1038/s41598-023-44540-6
work_keys_str_mv AT garazhianelahe decoratedgrapheneoxidewithgoldnanoparticlesasasensitivemodifiedcarbonpasteelectrodeforsimultaneousdeterminationoftyrosineanduricacid
AT kalatebojdimajid decoratedgrapheneoxidewithgoldnanoparticlesasasensitivemodifiedcarbonpasteelectrodeforsimultaneousdeterminationoftyrosineanduricacid
AT behbahanimohammad decoratedgrapheneoxidewithgoldnanoparticlesasasensitivemodifiedcarbonpasteelectrodeforsimultaneousdeterminationoftyrosineanduricacid