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Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid
It is presented here as a simple, selective, rapid, low-cost, with a wide linear range method to simultaneously determine tyrosine and uric acid using a modified carbon paste electrode decorated with graphene oxide and gold nanoparticles (GO/AuNPs/MCPE). In order to characterize and evaluate the mor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577133/ https://www.ncbi.nlm.nih.gov/pubmed/37840042 http://dx.doi.org/10.1038/s41598-023-44540-6 |
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author | Garazhian, Elahe Kalate Bojdi, Majid Behbahani, Mohammad |
author_facet | Garazhian, Elahe Kalate Bojdi, Majid Behbahani, Mohammad |
author_sort | Garazhian, Elahe |
collection | PubMed |
description | It is presented here as a simple, selective, rapid, low-cost, with a wide linear range method to simultaneously determine tyrosine and uric acid using a modified carbon paste electrode decorated with graphene oxide and gold nanoparticles (GO/AuNPs/MCPE). In order to characterize and evaluate the morphology and constituents of the nanostructures, X-ray diffraction spectroscopy, Transmission electron microscopes, Dynamic light scattering, Zeta potential, electrochemical impedance spectroscopy, and Voltammetry were employed. The current response on the surface of the modified electrode had a dynamic linear range relationship in the concentrations of 0.14–340.00 µmol L(−1) and 0.06–141.00 µmol L(−1) for tyrosine and uric acid, respectively, and the method detection limit (MDL) was 0.0060 µmol L(−1) and 0.0037 µmol L(−1), respectively. This modified electrode provided high stability, sensitivity, and acceptable reproducibility for voltammetric measurements of tyrosine and uric acid simultaneously in a biological matrix. |
format | Online Article Text |
id | pubmed-10577133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-105771332023-10-17 Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid Garazhian, Elahe Kalate Bojdi, Majid Behbahani, Mohammad Sci Rep Article It is presented here as a simple, selective, rapid, low-cost, with a wide linear range method to simultaneously determine tyrosine and uric acid using a modified carbon paste electrode decorated with graphene oxide and gold nanoparticles (GO/AuNPs/MCPE). In order to characterize and evaluate the morphology and constituents of the nanostructures, X-ray diffraction spectroscopy, Transmission electron microscopes, Dynamic light scattering, Zeta potential, electrochemical impedance spectroscopy, and Voltammetry were employed. The current response on the surface of the modified electrode had a dynamic linear range relationship in the concentrations of 0.14–340.00 µmol L(−1) and 0.06–141.00 µmol L(−1) for tyrosine and uric acid, respectively, and the method detection limit (MDL) was 0.0060 µmol L(−1) and 0.0037 µmol L(−1), respectively. This modified electrode provided high stability, sensitivity, and acceptable reproducibility for voltammetric measurements of tyrosine and uric acid simultaneously in a biological matrix. Nature Publishing Group UK 2023-10-15 /pmc/articles/PMC10577133/ /pubmed/37840042 http://dx.doi.org/10.1038/s41598-023-44540-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Garazhian, Elahe Kalate Bojdi, Majid Behbahani, Mohammad Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
title | Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
title_full | Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
title_fullStr | Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
title_full_unstemmed | Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
title_short | Decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
title_sort | decorated graphene oxide with gold nanoparticles as a sensitive modified carbon paste electrode for simultaneous determination of tyrosine and uric acid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577133/ https://www.ncbi.nlm.nih.gov/pubmed/37840042 http://dx.doi.org/10.1038/s41598-023-44540-6 |
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