Cargando…

The interplay of FLT3 and CXCR4 in acute myeloid leukemia: an ongoing debate

FLT3 mutations are very frequent in AML and utilization of FLT3 inhibitors as approved treatment options are very common. Despite the initial success of inhibitor treatment, the development of resistances against this treatment is a major challenge in AML therapy. One of the mechanisms causing resis...

Descripción completa

Detalles Bibliográficos
Autores principales: Klement, Laura, Drube, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577206/
https://www.ncbi.nlm.nih.gov/pubmed/37849810
http://dx.doi.org/10.3389/fonc.2023.1258679