Recent advances on cyclodepsipeptides: biologically active compounds for drug research

Cyclodepsipeptides are a large family of peptide-related natural products consisting of hydroxy and amino acids linked by amide and ester bonds. A number of cyclodepsipeptides have been isolated and characterized from fungi and bacteria. Most of them showed antitumor, antifungal, antiviral, antimala...

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Detalles Bibliográficos
Autores principales: Liu, Si-Xuan, Ou-Yang, Si-Yi, Lu, Yong-Fu, Guo, Chun-Lin, Dai, Si-Yang, Li, Chang, Yu, Tian-Yi, Pei, Yue-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577210/
https://www.ncbi.nlm.nih.gov/pubmed/37849925
http://dx.doi.org/10.3389/fmicb.2023.1276928
Descripción
Sumario:Cyclodepsipeptides are a large family of peptide-related natural products consisting of hydroxy and amino acids linked by amide and ester bonds. A number of cyclodepsipeptides have been isolated and characterized from fungi and bacteria. Most of them showed antitumor, antifungal, antiviral, antimalarial, and antitrypanosomal properties. Herein, this review summarizes the recent literatures (2010–2022) on the progress of cyclodepsipeptides from fungi and bacteria except for those of marine origin, in order to enrich our knowledge about their structural features and biological sources.

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