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SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline

Niche-derived growth factors support self-renewal of mouse spermatogonial stem and progenitor cells through ERK MAPK signaling and other pathways. At the same time, dysregulated growth factor-dependent signaling has been associated with loss of stem cell activity and aberrant differentiation. We hyp...

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Detalles Bibliográficos
Autores principales:	Luo, Yanyun, Yamada, Makiko, N’Tumba-Byn, Thierry, Asif, Hana, Gao, Meng, Hu, Yang, Marangoni, Pauline, Liu, Ying, Evans, Todd, Rafii, Shahin, Klein, Ophir D, Voss, Henning U, Hadjantonakis, Anna-Katerina, Elemento, Olivier, Martin, Laura A, Seandel, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577279/ https://www.ncbi.nlm.nih.gov/pubmed/37552049 http://dx.doi.org/10.1093/biolre/ioad089

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