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LncRP11-675F6.3 responds to rapamycin treatment and reduces triglyceride accumulation via interacting with HK1 in hepatocytes by regulating autophagy and VLDL-related proteins: LncRNA with HK1 regulates triglycerides, autophagy and VLDL

Long noncoding RNAs (lncRNAs) have been widely proven to be involved in liver lipid homeostasis. Herein, we identify an upregulated lncRNA named lncRP11-675F6.3 in response to rapamycin treatment using a microarray in HepG2 cells. Knockdown of lncRP11-675F6. 3 leads to a significant reduction in apo...

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Detalles Bibliográficos
Autores principales:	Wang, Lingling, Fang, Xiaojuan, Yang, Ziyou, Li, Xueling, Cheng, Mengdi, Cheng, Liang, Wang, Ganglin, Li, Wei, Liu, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577451/ https://www.ncbi.nlm.nih.gov/pubmed/37222534 http://dx.doi.org/10.3724/abbs.2023091

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