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Cooperative effects of SIRT1 and SIRT2 on APP acetylation

Alzheimer's disease (AD) is an age‐related neurodegenerative disorder characterized by amyloid‐β (Aβ) deposition and neurofibrillary tangles. Although the NAD(+)‐dependent deacetylases SIRT1 and SIRT2 play pivotal roles in age‐related diseases, their cooperative effects in AD have not yet been...

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Detalles Bibliográficos
Autores principales: Li, Na, Bai, Ning, Zhao, Xiong, Cheng, Rong, Wu, Xuan, Jiang, Bo, Li, Xiaoman, Xue, Mingli, Xu, Hongde, Guo, Qiqiang, Guo, Wendong, Ma, Mengtao, Cao, Sunrun, Feng, Yanling, Song, Xiaoyu, Wang, Zhuo, Zhang, Xiaoyu, Zou, Yu, Wang, Difei, Liu, Hua, Cao, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577574/
https://www.ncbi.nlm.nih.gov/pubmed/37602729
http://dx.doi.org/10.1111/acel.13967

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