Vaccine adjuvant-elicited CD8+ T cell immunity is co-dependent on T-bet and FOXO1

T-bet and FOXO1 are transcription factors canonically associated with effector and memory T cell fates, respectively. During an infectious response, these factors direct the development of CD8(+) T cell fates, where T-bet deficiency leads to ablation of only short-lived effector cells, while FOXO1 d...

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Detalles Bibliográficos
Autores principales: Ivanova, Daria L., Thompson, Scott B., Klarquist, Jared, Harbell, Michael G., Kilgore, Augustus M., Lasda, Erika L., Hesselberth, Jay R., Hunter, Christopher A., Kedl, Ross M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577800/
https://www.ncbi.nlm.nih.gov/pubmed/37516968
http://dx.doi.org/10.1016/j.celrep.2023.112911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577800/
https://www.ncbi.nlm.nih.gov/pubmed/37516968
http://dx.doi.org/10.1016/j.celrep.2023.112911

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