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Vaccine adjuvant-elicited CD8+ T cell immunity is co-dependent on T-bet and FOXO1
T-bet and FOXO1 are transcription factors canonically associated with effector and memory T cell fates, respectively. During an infectious response, these factors direct the development of CD8(+) T cell fates, where T-bet deficiency leads to ablation of only short-lived effector cells, while FOXO1 d...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577800/ https://www.ncbi.nlm.nih.gov/pubmed/37516968 http://dx.doi.org/10.1016/j.celrep.2023.112911 |