AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages

Tumor-associated macrophages (TAMs) are integral to the development of complex tumor microenvironments (TMEs) and can execute disparate cellular programs in response to extracellular cues. However, upstream signaling processes underpinning this phenotypic plasticity remain to be elucidated. Here, we...

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Detalles Bibliográficos
Autores principales: Hung, Chia-Nung, Chen, Meizhen, DeArmond, Daniel T., Chiu, Cheryl H.-L., Limboy, Catherine A., Tan, Xi, Kusi, Meena, Chou, Chih-Wei, Lin, Li-Ling, Zhang, Zhao, Wang, Chiou-Miin, Chen, Chun-Liang, Mitsuya, Kohzoh, Osmulski, Pawel A., Gaczynska, Maria E., Kirma, Nameer B., Vadlamudi, Ratna K., Gibbons, Don L., Warner, Steve, Brenner, Andrew J., Mahadevan, Daruka, Michalek, Joel E., Huang, Tim H.-M., Taverna, Josephine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577802/
https://www.ncbi.nlm.nih.gov/pubmed/37659081
http://dx.doi.org/10.1016/j.celrep.2023.113067

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