Cargando…

A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis

BACKGROUND: To evaluate the feature of different retinal layer segmentation in neuromyelitis optica spectrum disorders (NMOSD) with spectral-domain optical coherence tomography (SD-OCT) and to compare it with that in multiple sclerosis (MS), healthy controls (HC), and idiopathic optic neuritis (ION)...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Junxia, Tan, Shaoying, Peng, Chunxia, Zhou, Huanfen, Wei, Shihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577872/
https://www.ncbi.nlm.nih.gov/pubmed/37846392
http://dx.doi.org/10.1016/j.aopr.2021.100007
_version_ 1785121402333954048
author Fu, Junxia
Tan, Shaoying
Peng, Chunxia
Zhou, Huanfen
Wei, Shihui
author_facet Fu, Junxia
Tan, Shaoying
Peng, Chunxia
Zhou, Huanfen
Wei, Shihui
author_sort Fu, Junxia
collection PubMed
description BACKGROUND: To evaluate the feature of different retinal layer segmentation in neuromyelitis optica spectrum disorders (NMOSD) with spectral-domain optical coherence tomography (SD-OCT) and to compare it with that in multiple sclerosis (MS), healthy controls (HC), and idiopathic optic neuritis (ION). METHODS: We retrieved four electronic databases, including Pubmed, Embase, Cochrane Library, and Web of Science from inception to September 1st, 2021. A meta-analysis was performed to compare different retinal layer segmentation thicknesses between patients with or without a history of optic neuritis (ON) in NMOSD and the control group, including patients with MS, HC, and ION. RESULTS: Forty-two studies were included and the interval between the last ON onset and examination was greater than 3 months. Compared with that in HC eyes, the loss of retinal nerve fiber layer (RNFL) and macular ganglion cell and inner plexiform layer (GC-IPL) was serious in NMOSD eye especially after ON. Moreover, compared with that in ION eyes or MS-related-ON eyes, the injury to the peripapillary retinal nerve fiber layer (pRNFL) was severe in NMOSD-related-ON eyes. In addition, the correlation coefficient between pRNFL and prognostic visual acuity was 0.43. However, the one-arm study revealed the inner nuclear layer (INL) was thickened in NMOSD-related-ON eyes compared with HC eyes. CONCLUSIONS: Inclusion of the RNFL and macular GC-IPL is recommended for monitoring disease progression and attention should be paid to changes in the INL.
format Online
Article
Text
id pubmed-10577872
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-105778722023-10-16 A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis Fu, Junxia Tan, Shaoying Peng, Chunxia Zhou, Huanfen Wei, Shihui Adv Ophthalmol Pract Res Review BACKGROUND: To evaluate the feature of different retinal layer segmentation in neuromyelitis optica spectrum disorders (NMOSD) with spectral-domain optical coherence tomography (SD-OCT) and to compare it with that in multiple sclerosis (MS), healthy controls (HC), and idiopathic optic neuritis (ION). METHODS: We retrieved four electronic databases, including Pubmed, Embase, Cochrane Library, and Web of Science from inception to September 1st, 2021. A meta-analysis was performed to compare different retinal layer segmentation thicknesses between patients with or without a history of optic neuritis (ON) in NMOSD and the control group, including patients with MS, HC, and ION. RESULTS: Forty-two studies were included and the interval between the last ON onset and examination was greater than 3 months. Compared with that in HC eyes, the loss of retinal nerve fiber layer (RNFL) and macular ganglion cell and inner plexiform layer (GC-IPL) was serious in NMOSD eye especially after ON. Moreover, compared with that in ION eyes or MS-related-ON eyes, the injury to the peripapillary retinal nerve fiber layer (pRNFL) was severe in NMOSD-related-ON eyes. In addition, the correlation coefficient between pRNFL and prognostic visual acuity was 0.43. However, the one-arm study revealed the inner nuclear layer (INL) was thickened in NMOSD-related-ON eyes compared with HC eyes. CONCLUSIONS: Inclusion of the RNFL and macular GC-IPL is recommended for monitoring disease progression and attention should be paid to changes in the INL. Elsevier 2021-10-05 /pmc/articles/PMC10577872/ /pubmed/37846392 http://dx.doi.org/10.1016/j.aopr.2021.100007 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Fu, Junxia
Tan, Shaoying
Peng, Chunxia
Zhou, Huanfen
Wei, Shihui
A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis
title A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis
title_full A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis
title_fullStr A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis
title_full_unstemmed A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis
title_short A comparative study of alteration in retinal layer segmentation alteration by SD-OCT in neuromyelitis optica spectrum disorders: A systematic review and meta-analysis
title_sort comparative study of alteration in retinal layer segmentation alteration by sd-oct in neuromyelitis optica spectrum disorders: a systematic review and meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10577872/
https://www.ncbi.nlm.nih.gov/pubmed/37846392
http://dx.doi.org/10.1016/j.aopr.2021.100007
work_keys_str_mv AT fujunxia acomparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT tanshaoying acomparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT pengchunxia acomparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT zhouhuanfen acomparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT weishihui acomparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT fujunxia comparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT tanshaoying comparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT pengchunxia comparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT zhouhuanfen comparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis
AT weishihui comparativestudyofalterationinretinallayersegmentationalterationbysdoctinneuromyelitisopticaspectrumdisordersasystematicreviewandmetaanalysis