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Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications

BACKGROUND: Systemic lupus erythematosus (SLE) is known to be clinically heterogeneous. Previous efforts to characterize subsets of SLE patients based on gene expression analysis have not been reproduced because of small sample sizes or technical problems. The aim of this study was to develop a robu...

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Detalles Bibliográficos
Autores principales: Hubbard, Erika L., Bachali, Prathyusha, Kingsmore, Kathryn M., He, Yisha, Catalina, Michelle D., Grammer, Amrie C., Lipsky, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578040/
https://www.ncbi.nlm.nih.gov/pubmed/37845772
http://dx.doi.org/10.1186/s13073-023-01237-9