De novo design of monomeric helical bundles for pH‐controlled membrane lysis

Targeted intracellular delivery via receptor‐mediated endocytosis requires the delivered cargo to escape the endosome to prevent lysosomal degradation. This can in principle be achieved by membrane lysis tightly restricted to endosomal membranes upon internalization to avoid general membrane inserti...

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Detalles Bibliográficos
Autores principales: Goldbach, Nicolas, Benna, Issa, Wicky, Basile I. M., Croft, Jacob T., Carter, Lauren, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Sankaran, Banumathi, Yang, Erin C., Lee, Kelly K., Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578055/
https://www.ncbi.nlm.nih.gov/pubmed/37632837
http://dx.doi.org/10.1002/pro.4769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578055/
https://www.ncbi.nlm.nih.gov/pubmed/37632837
http://dx.doi.org/10.1002/pro.4769

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