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Expression of Endothelin-1, Endothelin Receptor-A, and Endothelin Receptor-B in facial melasma compared to adjacent skin

BACKGROUND/OBJECTIVES: Although melasma is highly prevalent, its pathogenesis is not yet fully understood. In the skin, endothelin-1 (ET-1) is primarily produced by keratinocytes in response to UVB exposure, which is mediated by an increase in IL-1α or reactive oxygen species. ET-1 plays a role in m...

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Detalles Bibliográficos
Autores principales:	da Silva, Carolina Nunhez, Miot, Hélio Amante, Grassi, Tony Fernando, Dias-Melício, Luciane Alarcão, Santos, Leandro, Espósito, Ana Cláudia Cavalcante
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578179/ https://www.ncbi.nlm.nih.gov/pubmed/37850109 http://dx.doi.org/10.2147/CCID.S402168

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