Cargando…
Molecular pharmacology of the onco-TRP channel TRPV6
TRPV6, a representative of the vanilloid subfamily of TRP channels, serves as the principal calcium uptake channel in the gut. Dysregulation of TRPV6 results in disturbed calcium homeostasis leading to a variety of human diseases, including many forms of cancer. Inhibitors of this oncochannel are th...
Autores principales: | Neuberger, Arthur, Sobolevsky, Alexander I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578198/ https://www.ncbi.nlm.nih.gov/pubmed/37838981 http://dx.doi.org/10.1080/19336950.2023.2266669 |
Ejemplares similares
-
Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6
por: Singh, Appu K., et al.
Publicado: (2018) -
Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB
por: Singh, Appu K., et al.
Publicado: (2018) -
Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine
por: Neuberger, Arthur, et al.
Publicado: (2022) -
Structural basis of temperature sensation by the TRP channel TRPV3
por: Singh, Appu K., et al.
Publicado: (2019) -
Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole
por: Neuberger, Arthur, et al.
Publicado: (2021)