Cargando…

TOMM40 ‘523 Genotype Distinguishes Patterns of Cognitive Improvement for Executive Function in APOE ɛ3 Homozygotes

BACKGROUND: TOMM40 ‘523 has been associated with cognitive performance and risk for developing Alzheimer’s disease independent of the effect of APOE genotype. Few studies have considered the longitudinal effect of this genotype on change in cognition over time. OBJECTIVE: Our objective was to evalua...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watts, Amber, Haneline, Stephen, Welsh-Bohmer, Kathleen A., Wu, Jingtao, Alexander, Robert, Swerdlow, Russell H., Burns, Daniel K., Saunders, Ann M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578241/ https://www.ncbi.nlm.nih.gov/pubmed/37718796 http://dx.doi.org/10.3233/JAD-230066

Ejemplares similares

APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans
por: Yu, Lei, et al.
Publicado: (2017)

Characterization of APOE and TOMM40 allele frequencies in the Japanese population
por: Nishimura, Akira, et al.
Publicado: (2017)

Use of local genetic ancestry to assess TOMM40-523′ and risk for Alzheimer disease
por: Bussies, Parker L., et al.
Publicado: (2020)

Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations
por: Linnertz, Colton, et al.
Publicado: (2012)

TOMM40‘523’ poly-T repeat length is a determinant of longitudinal cognitive decline in Parkinson’s disease
por: Bakeberg, Megan C., et al.
Publicado: (2021)

The TOMM40 ‘523’ polymorphism in disease risk and age of symptom onset in two independent cohorts of Parkinson’s disease
por: Bakeberg, Megan C., et al.
Publicado: (2021)

APOE/TOMM 40 genetic loci, white matter hyperintensities, and cerebral microbleeds
por: Lyall, Donald M., et al.
Publicado: (2015)

The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis
por: Gang, Qiang, et al.
Publicado: (2015)

Independent associations of TOMM40 and APOE variants with body mass index
por: Kulminski, Alexander M., et al.
Publicado: (2018)

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
por: Roses, A D, et al.
Publicado: (2010)

The influence of APOE and TOMM40 polymorphisms on hippocampal volume and episodic memory in old age
por: Ferencz, Beata, et al.
Publicado: (2013)

Superior Frontal Gyrus TOMM40-APOE Locus DNA Methylation in Alzheimer’s Disease
por: Bezuch, Natalia, et al.
Publicado: (2021)

Functional Analysis of APOE Locus Genetic Variation Implicates Regional Enhancers in the Regulation of Both TOMM40 and APOE
por: Bekris, L.M., et al.
Publicado: (2011)

Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936
por: Lyall, Donald M., et al.
Publicado: (2013)

Promising Genetic Biomarkers of Preclinical Alzheimer's Disease: The Influence of APOE and TOMM40 on Brain Integrity
por: Ferencz, Beata, et al.
Publicado: (2012)

Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?
por: Lyall, D M, et al.
Publicado: (2014)

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936()
por: Lyall, Donald M., et al.
Publicado: (2014)

Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia
por: Tang, Man-Hung Eric, et al.
Publicado: (2020)

APOE ɛ4 allele and TOMM40‐APOC1 variants jointly contribute to survival to older ages
por: Kulminski, Alexander M., et al.
Publicado: (2022)

A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases
por: Soyal, Selma M., et al.
Publicado: (2020)

Genetic Variants in PVRL2-TOMM40-APOE Region Are Associated with Human Longevity in a Han Chinese Population
por: Lu, Fang, et al.
Publicado: (2014)

Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
por: Kulminski, Alexander M., et al.
Publicado: (2022)

IMPACT OF COMBINATIONS OF THE APOE Ɛ4 ALLELE AND TOMM40-APOC1 VARIANTS ON SURVIVAL TO OLDER AGES AND ALZHEIMER’S RISK
por: Kulminski, Alexander, et al.
Publicado: (2022)

TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer’s Disease
por: Chen, Yi-Chun, et al.
Publicado: (2023)

Resistance to autosomal dominant Alzheimer’s in an APOE3-Christchurch homozygote: a case report
por: Arboleda-Velasquez, Joseph F., et al.
Publicado: (2019)

Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection
por: Henao‐Restrepo, Julián, et al.
Publicado: (2022)

Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits
por: Middelberg, Rita PS, et al.
Publicado: (2011)

Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE-ε4/TOMM40 long poly-T repeat allele variants
por: Prokopenko, Inga, et al.
Publicado: (2019)

Associations of Vascular Risk Factors, APOE and TOMM40 Polymorphisms With Cognitive Function in Dementia-Free Chinese Older Adults: A Community-Based Study
por: Gui, Wenjun, et al.
Publicado: (2021)

White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes
por: Operto, Grégory, et al.
Publicado: (2018)

Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes
por: Huq, Aamira J., et al.
Publicado: (2021)

TOMM40 RNA Transcription in Alzheimer’s Disease Brain and Its Implication in Mitochondrial Dysfunction
por: Lee, Eun-Gyung, et al.
Publicado: (2021)

TOMM40 genetic variants associated with healthy aging and longevity: a systematic review
por: Chen, Sunny, et al.
Publicado: (2022)

Recovery and sequelae in 523 adults and children with tick-borne encephalitis in Germany
por: Nygren, Teresa M., et al.
Publicado: (2023)

Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis
por: Bracher-Smith, Matthew, et al.
Publicado: (2022)

Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of APOE4 Homozygotes and Non-APOE4 Carriers with Mild Cognitive Impairment versus Subjective Cognitive Decline
por: den Hoedt, Sandra, et al.
Publicado: (2023)

Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population
por: Radovica, I., et al.
Publicado: (2014)

BCL3-PVRL2-TOMM40 SNPs, gene-gene and gene-environment interactions on dyslipidemia
por: Miao, Liu, et al.
Publicado: (2018)

Biothiols and oxidative stress markers and polymorphisms of TOMM40 and APOC1 genes in Alzheimer’s disease patients
por: Prendecki, Michal, et al.
Publicado: (2018)

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
por: Reiman, Eric M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hjj6ium3utsmtv98j61eciehak