Cargando…

Comprehensive analysis of crystal structure, spectroscopic properties, quantum chemical insights, and molecular docking studies of two pyrazolopyridine compounds: potential anticancer agents

In this study, two pyrazolo[3,4-b]pyridine derivatives (4a and 4b) were grown using a slow evaporation solution growth technique and characterized by FT-IR, HRMS, (1)H/(13)C NMR spectroscopy, and X-ray crystallography. The 4a and 4b structures crystallized in monoclinic and triclinic systems with sp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Polo-Cuadrado, Efraín, López-Cuellar, Lorena, Acosta-Quiroga, Karen, Rojas-Peña, Cristian, Brito, Iván, Cisterna, Jonathan, Trilleras, Jorge, Alderete, Joel B., Duarte, Yorley, Gutiérrez, Margarita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578360/ https://www.ncbi.nlm.nih.gov/pubmed/37849708 http://dx.doi.org/10.1039/d3ra04874h

Ejemplares similares

Design, synthesis, theoretical study, antioxidant, and anticholinesterase activities of new pyrazolo-fused phenanthrolines
por: Polo-Cuadrado, Efraín, et al.
Publicado: (2022)

Piperonal chalcone derivative incorporating the pyrazolo[3,4-b]pyridine moiety; crystal structure, spectroscopic characterization and quantum chemical investigations
por: Polo-Cuadrado, Efraín, et al.
Publicado: (2023)

Efficient MW-Assisted Synthesis, Spectroscopic Characterization, X-ray and Antioxidant Properties of Indazole Derivatives
por: Polo, Efrain, et al.
Publicado: (2016)

Spirocyclic derivatives as antioxidants: a review
por: Acosta-Quiroga, Karen, et al.
Publicado: (2021)

Synthesis and antimalarial potential of some novel quinoline-pyrazolopyridine derivatives
por: Saini, Deepika, et al.
Publicado: (2016)

Discovery of New Pyrazolopyridine, Furopyridine, and Pyridine Derivatives as CDK2 Inhibitors: Design, Synthesis, Docking Studies, and Anti-Proliferative Activity
por: Abdel-Rahman, Adel A.-H., et al.
Publicado: (2021)

Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction
por: Murlykina, Maryna V, et al.
Publicado: (2019)

The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines
por: C. S. Pinheiro, Luiz, et al.
Publicado: (2019)

Barbiturates and pyrazolopyridines for the treatment of postpartum depression—repurposing of two drug classes
por: Horwitz, Alexander B., et al.
Publicado: (2023)

Efficient synthesis of pyrazolopyridines containing a chromane backbone through domino reaction
por: Navari, Razieh, et al.
Publicado: (2019)

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach
por: Wani, Tanveer A., et al.
Publicado: (2018)

The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 In Vitro Replicative Cycle
por: Miranda, Milene D., et al.
Publicado: (2022)

Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking
por: Cuartas, Viviana, et al.
Publicado: (2021)

Direct Oral FXa Inhibitors Binding to Human Serum Albumin: Spectroscopic, Calorimetric, and Computational Studies
por: Mariño-Ocampo, Nory, et al.
Publicado: (2023)

Effectiveness of a bio-catalytic agent used in the bioremediation of crude oil-polluted seawater
por: Teran-Cuadrado, Glenda, et al.
Publicado: (2021)

Urease covalently immobilized on cotton-derived nanocellulose-dialdehyde for urea detection and urea-based multicomponent synthesis of tetrahydro-pyrazolopyridines in water
por: Tamaddon, Fatemeh, et al.
Publicado: (2019)

Inhibition of Tyrosinase by Mercury Chloride: Spectroscopic and Docking Studies
por: Chen, Jianmin, et al.
Publicado: (2020)

Synthesis, Spectroscopic, Structural and Molecular Docking Studies of Some New Nano-Sized Ferrocene-Based Imine Chelates as Antimicrobial and Anticancer Agents
por: Khalaf, Mai M., et al.
Publicado: (2022)

Designing metal chelates of halogenated sulfonamide Schiff bases as potent nonplatinum anticancer drugs using spectroscopic, molecular docking and biological studies
por: Elsamra, Rehab M. I., et al.
Publicado: (2022)

New pyrazolopyridine and pyrazolothiazole-based compounds as anti-proliferative agents targeting c-Met kinase inhibition: design, synthesis, biological evaluation, and computational studies
por: Alamshany, Zahra M., et al.
Publicado: (2023)

Spectroscopic and Docking Studies on the Binding of Liquiritigenin with Hyaluronidase for Antiallergic Mechanism
por: Zeng, Hua-jin, et al.
Publicado: (2016)

Synthesis of Bistetrahydroquinolines as Potential Anticholinesterasic Agents by Double Diels-Alder Reactions
por: Duarte, Yorley, et al.
Publicado: (2013)

Interaction of repaglinide with bovine serum albumin: Spectroscopic and molecular docking approaches
por: Pawar, Suma K., et al.
Publicado: (2019)

Interaction Behavior Between Niclosamide and Pepsin Determined by Spectroscopic and Docking Methods
por: Guo, Liuqi, et al.
Publicado: (2015)

Elucidation of DNA-Eltrombopag Binding: Electrochemical, Spectroscopic and Molecular Docking Techniques
por: Cheraghi, Somaye, et al.
Publicado: (2023)

Facile synthesis of pyrazolopyridine pharmaceuticals under mild conditions using an algin-functionalized silica-based magnetic nanocatalyst (Alg@SBA-15/Fe(3)O(4))
por: Hassanzadeh-Afruzi, Fereshte, et al.
Publicado: (2023)

A Novel Class of Selective Acetylcholinesterase Inhibitors: Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles
por: de la Torre, Pedro, et al.
Publicado: (2012)

Cobaltoceniumselenolate Gold(I) Complexes: Synthesis, Spectroscopic, Structural and Anticancer Properties
por: Menia, Daniel, et al.
Publicado: (2021)

Thiopurines Analogues with Additional Ring: Synthesis, Spectroscopic Properties, and Anticancer Potency
por: Krancewicz, Katarzyna, et al.
Publicado: (2023)

Spectroscopic, Biological, and Topological Insights on Lemonol as a Potential Anticancer Agent
por: Ram Kumar, A., et al.
Publicado: (2023)

Experimental and Theoretical Approaches in the Study of Phenanthroline‐Tetrahydroquinolines for Alzheimer's Disease
por: Duarte, Yorley, et al.
Publicado: (2019)

Spectroscopic and Molecular Docking Investigation on the Noncovalent Interaction of Lysozyme with Saffron Constituent “Safranal”
por: Ali, Mohd. Sajid, et al.
Publicado: (2020)

Spectroscopic, Thermodynamic and Molecular Docking Studies on Molecular Mechanisms of Drug Binding to Proteins
por: Wani, Tanveer A., et al.
Publicado: (2022)

Characterization of the Interactions between Minocycline Hydrochloride and Trypsin with Spectroscopic and Molecular Docking Technology
por: Wang, Xiaoxia, et al.
Publicado: (2023)

Novel 4-Azapregnene Derivatives as Potential Anticancer Agents: Synthesis, Antiproliferative Activity and Molecular Docking Studies
por: Brito, Vanessa, et al.
Publicado: (2022)

Mesoporous halloysite nanotubes modified by CuFe(2)O(4) spinel ferrite nanoparticles and study of its application as a novel and efficient heterogeneous catalyst in the synthesis of pyrazolopyridine derivatives
por: Maleki, Ali, et al.
Publicado: (2019)

Molecular Docking Compounds of Cinnamaldehyde Derivatives as Anticancer Agents
por: Warsito, Warsito, et al.
Publicado: (2021)

Synthesis, spectroscopic, dielectric, molecular docking and DFT studies of (3E)-3-(4-methylbenzylidene)-3,4-dihydro-2H-chromen-2-one: an anticancer agent
por: Beena, T., et al.
Publicado: (2017)

Investigation of the Interaction of Naringin Palmitate with Bovine Serum Albumin: Spectroscopic Analysis and Molecular Docking
por: Zhang, Xia, et al.
Publicado: (2013)

Study on the interaction of paeoniflorin with human serum albumin (HSA) by spectroscopic and molecular docking techniques
por: Xu, Liang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_du7fsi8m6dusggtrus7njlenf3