Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia

COVID-19 is a systemic disease associated with respiratory insufficiency, systemic inflammation, as well as coagulation, neurological, and endocrine disorders. Among them pituitary apoplexy (PA) as well as, more rarely, acute hypophysitis (AH) have been reported. In the present report, we described...

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Detalles Bibliográficos
Autores principales: Racca, Giulia, D’Agnano, Salvatore, Fasano, Nicoletta, Gianotti, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578393/
https://www.ncbi.nlm.nih.gov/pubmed/37908272
http://dx.doi.org/10.1210/jcemcr/luac010
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author Racca, Giulia
D’Agnano, Salvatore
Fasano, Nicoletta
Gianotti, Laura
author_facet Racca, Giulia
D’Agnano, Salvatore
Fasano, Nicoletta
Gianotti, Laura
author_sort Racca, Giulia
collection PubMed
description COVID-19 is a systemic disease associated with respiratory insufficiency, systemic inflammation, as well as coagulation, neurological, and endocrine disorders. Among them pituitary apoplexy (PA) as well as, more rarely, acute hypophysitis (AH) have been reported. In the present report, we described a case of PA in an 84-year-old man with SARS-CoV-2 pneumonia, with a previous unknown pituitary adenoma and a possible but not confirmed overlap with transitory AH. After reviewing the available literature, we discuss the potential clinical and pathophysiological relationship between PA and AH. Furthermore, we focus on the neuroradiological features of pituitary lesions in the presence of SARS-CoV-2 infection.
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spelling pubmed-105783932023-10-31 Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia Racca, Giulia D’Agnano, Salvatore Fasano, Nicoletta Gianotti, Laura JCEM Case Rep Case Report COVID-19 is a systemic disease associated with respiratory insufficiency, systemic inflammation, as well as coagulation, neurological, and endocrine disorders. Among them pituitary apoplexy (PA) as well as, more rarely, acute hypophysitis (AH) have been reported. In the present report, we described a case of PA in an 84-year-old man with SARS-CoV-2 pneumonia, with a previous unknown pituitary adenoma and a possible but not confirmed overlap with transitory AH. After reviewing the available literature, we discuss the potential clinical and pathophysiological relationship between PA and AH. Furthermore, we focus on the neuroradiological features of pituitary lesions in the presence of SARS-CoV-2 infection. Oxford University Press 2022-11-29 /pmc/articles/PMC10578393/ /pubmed/37908272 http://dx.doi.org/10.1210/jcemcr/luac010 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Racca, Giulia
D’Agnano, Salvatore
Fasano, Nicoletta
Gianotti, Laura
Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia
title Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia
title_full Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia
title_fullStr Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia
title_full_unstemmed Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia
title_short Pituitary Apoplexy With Transition to Acute Hypophysitis in a Patient With Sars-CoV-2 Pneumonia
title_sort pituitary apoplexy with transition to acute hypophysitis in a patient with sars-cov-2 pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578393/
https://www.ncbi.nlm.nih.gov/pubmed/37908272
http://dx.doi.org/10.1210/jcemcr/luac010
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