Targeting the pericyte antigen DLK1 with an alpha type-1 polarized dendritic cell vaccine results in tumor vascular modulation and protection against colon cancer progression

Despite the availability of various treatment options, colorectal cancer (CRC) remains a significant contributor to cancer-related mortality. Current standard-of-care interventions, including surgery, chemotherapy, and targeted agents like immune checkpoint blockade and anti-angiogenic therapies, ha...

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Detalles Bibliográficos
Autores principales: McCormick, Amanda L., Anderson, Trevor S., Daugherity, Elizabeth A., Okpalanwaka, Izuchukwu F., Smith, Savanna L., Appiah, Duke, Lowe, Devin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578441/
https://www.ncbi.nlm.nih.gov/pubmed/37849752
http://dx.doi.org/10.3389/fimmu.2023.1241949

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