Small-molecule Ro-08-2750 interacts with many RNA-binding proteins and elicits MUSASHI2-independent phenotypes

RNA-binding proteins (RBPs) are key regulators of gene expression. Small molecules targeting these RBP–RNA interactions are a rapidly emerging class of therapeutics for treating a variety of diseases. Ro-08-2750 (Ro) is a small molecule identified as a competitive inhibitor of Musashi (MSI)–RNA inte...

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Detalles Bibliográficos
Autores principales: Walters, Kathryn, Sajek, Marcin Piotr, Murphy, Elisabeth, Issaian, Aaron, Baldwin, Amber, Harrison, Evan, Daniels, Miles, Reisz, Julie A., Hansen, Kirk, D'Alessandro, Angelo, Mukherjee, Neelanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578479/
https://www.ncbi.nlm.nih.gov/pubmed/37369529
http://dx.doi.org/10.1261/rna.079605.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578479/
https://www.ncbi.nlm.nih.gov/pubmed/37369529
http://dx.doi.org/10.1261/rna.079605.123

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