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Small-molecule Ro-08-2750 interacts with many RNA-binding proteins and elicits MUSASHI2-independent phenotypes
RNA-binding proteins (RBPs) are key regulators of gene expression. Small molecules targeting these RBP–RNA interactions are a rapidly emerging class of therapeutics for treating a variety of diseases. Ro-08-2750 (Ro) is a small molecule identified as a competitive inhibitor of Musashi (MSI)–RNA inte...
Autores principales: | Walters, Kathryn, Sajek, Marcin Piotr, Murphy, Elisabeth, Issaian, Aaron, Baldwin, Amber, Harrison, Evan, Daniels, Miles, Reisz, Julie A., Hansen, Kirk, D'Alessandro, Angelo, Mukherjee, Neelanjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578479/ https://www.ncbi.nlm.nih.gov/pubmed/37369529 http://dx.doi.org/10.1261/rna.079605.123 |
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