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Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia

Roux-en-Y cholangiojejunostomy is a standard procedure for biliary reconstruction in pediatric living donor liver transplantation (LDLT). However, there is uncertainty on whether the adult standard of Roux branch limb is suitable for pediatric LDLT and its impact on postoperative biliary complicatio...

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Detalles Bibliográficos
Autores principales: Zhang, Yuhong, Zhu, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578680/
https://www.ncbi.nlm.nih.gov/pubmed/37832085
http://dx.doi.org/10.1097/MD.0000000000035396
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author Zhang, Yuhong
Zhu, Zhijun
author_facet Zhang, Yuhong
Zhu, Zhijun
author_sort Zhang, Yuhong
collection PubMed
description Roux-en-Y cholangiojejunostomy is a standard procedure for biliary reconstruction in pediatric living donor liver transplantation (LDLT). However, there is uncertainty on whether the adult standard of Roux branch limb is suitable for pediatric LDLT and its impact on postoperative biliary complications (BC). This study aimed to explore the effect of the short Roux limb and standard limb on pediatric LDLT biliary reconstruction. According to the length of the Roux limb, 168 LDLT children were divided into the routine limb group (n = 108) and the short limb group (n = 60). The incidences of postoperative biliary tract complications between the 2 groups were compared retrospectively. The mean Roux limb length in the short limb group was significantly shorter than that in the routine limb group group (P < .01). There were significant differences in age, height, and weight between the 2 groups (P < .01). However, there were no significant differences in graft-to-recipient weight ratio, intraoperative blood loss, cold ischemia time, and operation time between the 2 groups (P > .01). Moreover, postoperative BC, including refluxing cholangitis, were similar between the 2 groups (P = .876). Furthermore, the history of Kasai surgery, the history of postoperative RC of Kasai, and whether or not the Roux limb was reconstructed had no significant effect on the occurrence of postoperative RC. There was no significant difference in postoperative BC between the short limb and the routine limb in children with living donor liver transplantation.
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spelling pubmed-105786802023-10-17 Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia Zhang, Yuhong Zhu, Zhijun Medicine (Baltimore) 6200 Roux-en-Y cholangiojejunostomy is a standard procedure for biliary reconstruction in pediatric living donor liver transplantation (LDLT). However, there is uncertainty on whether the adult standard of Roux branch limb is suitable for pediatric LDLT and its impact on postoperative biliary complications (BC). This study aimed to explore the effect of the short Roux limb and standard limb on pediatric LDLT biliary reconstruction. According to the length of the Roux limb, 168 LDLT children were divided into the routine limb group (n = 108) and the short limb group (n = 60). The incidences of postoperative biliary tract complications between the 2 groups were compared retrospectively. The mean Roux limb length in the short limb group was significantly shorter than that in the routine limb group group (P < .01). There were significant differences in age, height, and weight between the 2 groups (P < .01). However, there were no significant differences in graft-to-recipient weight ratio, intraoperative blood loss, cold ischemia time, and operation time between the 2 groups (P > .01). Moreover, postoperative BC, including refluxing cholangitis, were similar between the 2 groups (P = .876). Furthermore, the history of Kasai surgery, the history of postoperative RC of Kasai, and whether or not the Roux limb was reconstructed had no significant effect on the occurrence of postoperative RC. There was no significant difference in postoperative BC between the short limb and the routine limb in children with living donor liver transplantation. Lippincott Williams & Wilkins 2023-10-13 /pmc/articles/PMC10578680/ /pubmed/37832085 http://dx.doi.org/10.1097/MD.0000000000035396 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 6200
Zhang, Yuhong
Zhu, Zhijun
Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia
title Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia
title_full Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia
title_fullStr Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia
title_full_unstemmed Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia
title_short Short limb in biliary tract reconstruction: A retrospective study of living donor liver transplantation in children with biliary atresia
title_sort short limb in biliary tract reconstruction: a retrospective study of living donor liver transplantation in children with biliary atresia
topic 6200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578680/
https://www.ncbi.nlm.nih.gov/pubmed/37832085
http://dx.doi.org/10.1097/MD.0000000000035396
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