Cargando…

Lactulose in cirrhosis: Current understanding of efficacy, mechanism, and practical considerations

HE is a complication of cirrhosis characterized by neuropsychiatric and motor dysfunction, and results in decreased quality of life and increased mortality. Lactulose is a synthetic disaccharide used to treat HE since 1966, though many questions about its use remain unanswered. Lactulose reverses mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bloom, Patricia P., Tapper, Elliot B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578757/ https://www.ncbi.nlm.nih.gov/pubmed/37820287 http://dx.doi.org/10.1097/HC9.0000000000000295

Ejemplares similares

Profile of Hepatic Encephalopathy in Children with Cirrhosis and Response to Lactulose
por: Sharma, Praveen, et al.
Publicado: (2011)

Real-World Experience of the One-Year Efficacy of Rifaximin Add-On to Lactulose Is Superior to Lactulose Alone in Patients with Cirrhosis Complicated with Recurrent Hepatic Encephalopathy in Taiwan
por: Chang, Ching, et al.
Publicado: (2021)

Faecal bacterial microbiota in patients with cirrhosis and the effect of lactulose administration
por: Sarangi, Aditya Narayan, et al.
Publicado: (2017)

How Do Patients With Cirrhosis and Their Caregivers Learn About and Manage Their Health? A Review and Qualitative Study
por: Saleh, Zachary M., et al.
Publicado: (2020)

Polyethylene Glycol and Lactulose versus Lactulose Alone in the Treatment of Hepatic Encephalopathy in Patients with Cirrhosis: A Non-Inferiority Randomized Controlled Trial
por: Naderian, Mohammadreza, et al.
Publicado: (2017)

Review article: current and emerging therapies for the management of cirrhosis and its complications
por: Tapper, Elliot B., et al.
Publicado: (2022)

The Hepatic Coma Syndromes and Lactulose
por: Elias, Elwyn
Publicado: (1979)

Cirrhosis and autoimmune liver disease: Current understanding
por: Liberal, Rodrigo, et al.
Publicado: (2016)

Combination of rifaximin and lactulose improves clinical efficacy and mortality in patients with hepatic encephalopathy
por: Wang, Zhida, et al.
Publicado: (2018)

Efficacy and safety of lactulose for the treatment of irritable bowel syndrome
por: Chen, Hong-Bin, et al.
Publicado: (2019)

Lactulose, Disaccharides and Colonic Flora: Clinical Consequences
por: Clausen, Mette Rye, et al.
Publicado: (2012)

The Use of Administrative Data to Investigate the Population Burden of Hepatic Encephalopathy
por: Bloom, Patricia P., et al.
Publicado: (2020)

Interventions to improve physical function and prevent adverse events in cirrhosis
por: Trivedi, Hirsh D, et al.
Publicado: (2018)

Reevaluating our understanding of lactulose breath tests by incorporating hydrogen sulfide measurements
por: Birg, Aleksandr, et al.
Publicado: (2019)

The efficacy and safety profile of albumin administration for patients with cirrhosis at high risk of hepatorenal syndrome is dose dependent
por: Afinogenova, Yuliya, et al.
Publicado: (2015)

Reversal of Low-Grade Cerebral Edema After Lactulose/Rifaximin Therapy in Patients with Cirrhosis and Minimal Hepatic Encephalopathy
por: Rai, Rahul, et al.
Publicado: (2015)

The Efficacy of Lactulose for the Treatment of Hyperammonemic Encephalopathy Due to Severe Heart Failure
por: Narita, Koichi, et al.
Publicado: (2020)

Efficacy and Mechanism of Trimebutine Maleate Combined with Lactulose in the Treatment of Constipation-Predominant Irritable Bowel Syndrome in the Elderly
por: Zhou, Yeping, et al.
Publicado: (2022)

Design and application of a lactulose biosensor
por: Wu, Jieyuan, et al.
Publicado: (2017)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain
por: Holman, Alexis, et al.
Publicado: (2023)

Lactulose:Mannitol Diagnostic Test by HPLC and LC-MSMS Platforms: Considerations for Field Studies of Intestinal Barrier Function and Environmental Enteropathy
por: Lee, Gwenyth O., et al.
Publicado: (2014)

Co-Administration of Lactulose Crystals with Amoxicillin Followed by Prolonged Lactulose Treatment Promotes Recovery of the Human Gut Microbiome In Vitro
por: Duysburgh, Cindy, et al.
Publicado: (2022)

The effect of lactulose in prevention of ventilator associated pneumonia (VAP)
por: Zvonicek, V, et al.
Publicado: (2001)

Evaluation of lactulose, lactose, and fructose breath testing in clinical practice: A focus on methane
por: Harvie, Ruth M, et al.
Publicado: (2019)

Friend or Foe? Spontaneous Portosystemic Shunts in Cirrhosis—Current Understanding and Future Prospects
por: Rajesh, Sasidharan, et al.
Publicado: (2021)

Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations
por: Wang, Jian, et al.
Publicado: (2021)

Awake Proning: Current Evidence and Practical Considerations
por: Sodhi, Kanwalpreet, et al.
Publicado: (2020)

Long-term management of hepatic encephalopathy with lactulose and/or rifaximin: a review of the evidence
por: Hudson, Mark, et al.
Publicado: (2019)

Multistrain probiotic and lactulose in the treatment of minimal hepatic encephalopathy
por: Shavakhi, Ahmad, et al.
Publicado: (2014)

Carnitine/cyclophosphamide/lactulose: Various toxicities: case report
Publicado: (2019)

Lactulose/rifaximin: Lack of drug effect: case report
Publicado: (2021)

The potential role of lactulose pharmacotherapy in the treatment and prevention of diabetes
por: Chu, Natural, et al.
Publicado: (2022)

The emotional burden of caregiving for patients with cirrhosis
por: Saleh, Zachary M., et al.
Publicado: (2022)

Current understanding of reovirus oncolysis mechanisms
por: Phillips, Matthew B, et al.
Publicado: (2018)

The incidence and outcome of postoperative hepatic encephalopathy in patients with cirrhosis
por: Saleh, Zachary M., et al.
Publicado: (2021)

Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study
por: Tapper, Elliot B, et al.
Publicado: (2018)

The COVID-19 pandemic will have a long-lasting impact on the quality of cirrhosis care
por: Tapper, Elliot B., et al.
Publicado: (2020)

Current Applications of Metabolomics in Cirrhosis
por: Khan, Vinshi, et al.
Publicado: (2018)

Deprescribing zolpidem reduces falls and fractures in patients with cirrhosis
por: Tapper, Elliot B., et al.
Publicado: (2022)

Alterations in the intestinal microbiome and metabolic profile of patients with cirrhosis supplemented with lactulose, Clostridium butyricum, and Bifidobacterium longum infantis: a randomized placebo-controlled trial
por: Lu, Haifeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e2g0m6jnd2dfvmbjccig2vvkjs