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Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
INTRODUCTION: achalasia is a chronic disease. Since there is no curative treatment, diagnosed patients have pharmacological and/or surgical techniques available, aimed at minimizing the condition. POEM appears as a promising new type of palliative treatment with good rates of symptom improvement. OB...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgiões
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578864/ https://www.ncbi.nlm.nih.gov/pubmed/36629719 http://dx.doi.org/10.1590/0100-6991e-20223244-en |
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author | FRANÇA, IGOR RABELO DE CALDAS, EDUARDA AUGUSTA DE LUCENA BARROS, MARCELLA FERREIRA SILVA, JOSE TARCÍSIO DIAS DA PONTUAL, JOÃO PAULO FERRAZ, ÁLVARO A. B. |
author_facet | FRANÇA, IGOR RABELO DE CALDAS, EDUARDA AUGUSTA DE LUCENA BARROS, MARCELLA FERREIRA SILVA, JOSE TARCÍSIO DIAS DA PONTUAL, JOÃO PAULO FERRAZ, ÁLVARO A. B. |
author_sort | FRANÇA, IGOR RABELO DE |
collection | PubMed |
description | INTRODUCTION: achalasia is a chronic disease. Since there is no curative treatment, diagnosed patients have pharmacological and/or surgical techniques available, aimed at minimizing the condition. POEM appears as a promising new type of palliative treatment with good rates of symptom improvement. OBJECTIVE: evaluate the profile of POEM at the Clinical Hospital of the Federal University of Pernambuco (HC - UFPE) and correlate it with the world scenario. METHODS: data collection was performed retrospectively from September 2017 to October 2019 with all patients undergoing POEM at the HC - UFPE. Sociodemographic, clinical, and hospital variables were evaluated before and three months after the procedure. RESULTS: of 27 patients (52.41 ± 19.24 years old) who underwent the procedure, 66.7% had idiopathic etiology and 33.3% had etiology secondary to Chagas disease. 48% patients underwent previous procedures, of which seven used some type of medication for symptom control, two underwent pneumatic endoscopic dilation, and four underwent Heller cardiomyotomy with partial fundoplication. 62.5% of the evaluated patients had type II achalasia before the procedure. Seven (25.9%) patients presented the following adverse events: four presented bleeding, two pneumoperitoneum, and one both complications, all being treated conservatively. The Eckardt score reduced from 8.37 ± 1.45 to 0.85 ± 1.06 (p-value <0.001). CONCLUSION: clinical improvement of symptoms and the patient profile followed the worldwide trend, with emphasis on the etiology secondary to Chagas disease, endemic in Brazil. Gastroesophageal reflux remains the main post-operative symptom. |
format | Online Article Text |
id | pubmed-10578864 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Colégio Brasileiro de Cirurgiões |
record_format | MEDLINE/PubMed |
spelling | pubmed-105788642023-10-17 Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term FRANÇA, IGOR RABELO DE CALDAS, EDUARDA AUGUSTA DE LUCENA BARROS, MARCELLA FERREIRA SILVA, JOSE TARCÍSIO DIAS DA PONTUAL, JOÃO PAULO FERRAZ, ÁLVARO A. B. Rev Col Bras Cir Original Article INTRODUCTION: achalasia is a chronic disease. Since there is no curative treatment, diagnosed patients have pharmacological and/or surgical techniques available, aimed at minimizing the condition. POEM appears as a promising new type of palliative treatment with good rates of symptom improvement. OBJECTIVE: evaluate the profile of POEM at the Clinical Hospital of the Federal University of Pernambuco (HC - UFPE) and correlate it with the world scenario. METHODS: data collection was performed retrospectively from September 2017 to October 2019 with all patients undergoing POEM at the HC - UFPE. Sociodemographic, clinical, and hospital variables were evaluated before and three months after the procedure. RESULTS: of 27 patients (52.41 ± 19.24 years old) who underwent the procedure, 66.7% had idiopathic etiology and 33.3% had etiology secondary to Chagas disease. 48% patients underwent previous procedures, of which seven used some type of medication for symptom control, two underwent pneumatic endoscopic dilation, and four underwent Heller cardiomyotomy with partial fundoplication. 62.5% of the evaluated patients had type II achalasia before the procedure. Seven (25.9%) patients presented the following adverse events: four presented bleeding, two pneumoperitoneum, and one both complications, all being treated conservatively. The Eckardt score reduced from 8.37 ± 1.45 to 0.85 ± 1.06 (p-value <0.001). CONCLUSION: clinical improvement of symptoms and the patient profile followed the worldwide trend, with emphasis on the etiology secondary to Chagas disease, endemic in Brazil. Gastroesophageal reflux remains the main post-operative symptom. Colégio Brasileiro de Cirurgiões 2022-12-02 /pmc/articles/PMC10578864/ /pubmed/36629719 http://dx.doi.org/10.1590/0100-6991e-20223244-en Text en © 2022 Revista do Colégio Brasileiro de Cirurgiões https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article FRANÇA, IGOR RABELO DE CALDAS, EDUARDA AUGUSTA DE LUCENA BARROS, MARCELLA FERREIRA SILVA, JOSE TARCÍSIO DIAS DA PONTUAL, JOÃO PAULO FERRAZ, ÁLVARO A. B. Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term |
title | Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term |
title_full | Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term |
title_fullStr | Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term |
title_full_unstemmed | Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term |
title_short | Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term |
title_sort | peroral endoscopic myotomy for the treatment of achalasia in the unified healthcare system (sus): results of a short-term |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578864/ https://www.ncbi.nlm.nih.gov/pubmed/36629719 http://dx.doi.org/10.1590/0100-6991e-20223244-en |
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