Cargando…

Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term

INTRODUCTION: achalasia is a chronic disease. Since there is no curative treatment, diagnosed patients have pharmacological and/or surgical techniques available, aimed at minimizing the condition. POEM appears as a promising new type of palliative treatment with good rates of symptom improvement. OB...

Descripción completa

Detalles Bibliográficos
Autores principales: FRANÇA, IGOR RABELO DE, CALDAS, EDUARDA AUGUSTA DE LUCENA, BARROS, MARCELLA FERREIRA, SILVA, JOSE TARCÍSIO DIAS DA, PONTUAL, JOÃO PAULO, FERRAZ, ÁLVARO A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgiões 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578864/
https://www.ncbi.nlm.nih.gov/pubmed/36629719
http://dx.doi.org/10.1590/0100-6991e-20223244-en
_version_ 1785121603855581184
author FRANÇA, IGOR RABELO DE
CALDAS, EDUARDA AUGUSTA DE LUCENA
BARROS, MARCELLA FERREIRA
SILVA, JOSE TARCÍSIO DIAS DA
PONTUAL, JOÃO PAULO
FERRAZ, ÁLVARO A. B.
author_facet FRANÇA, IGOR RABELO DE
CALDAS, EDUARDA AUGUSTA DE LUCENA
BARROS, MARCELLA FERREIRA
SILVA, JOSE TARCÍSIO DIAS DA
PONTUAL, JOÃO PAULO
FERRAZ, ÁLVARO A. B.
author_sort FRANÇA, IGOR RABELO DE
collection PubMed
description INTRODUCTION: achalasia is a chronic disease. Since there is no curative treatment, diagnosed patients have pharmacological and/or surgical techniques available, aimed at minimizing the condition. POEM appears as a promising new type of palliative treatment with good rates of symptom improvement. OBJECTIVE: evaluate the profile of POEM at the Clinical Hospital of the Federal University of Pernambuco (HC - UFPE) and correlate it with the world scenario. METHODS: data collection was performed retrospectively from September 2017 to October 2019 with all patients undergoing POEM at the HC - UFPE. Sociodemographic, clinical, and hospital variables were evaluated before and three months after the procedure. RESULTS: of 27 patients (52.41 ± 19.24 years old) who underwent the procedure, 66.7% had idiopathic etiology and 33.3% had etiology secondary to Chagas disease. 48% patients underwent previous procedures, of which seven used some type of medication for symptom control, two underwent pneumatic endoscopic dilation, and four underwent Heller cardiomyotomy with partial fundoplication. 62.5% of the evaluated patients had type II achalasia before the procedure. Seven (25.9%) patients presented the following adverse events: four presented bleeding, two pneumoperitoneum, and one both complications, all being treated conservatively. The Eckardt score reduced from 8.37 ± 1.45 to 0.85 ± 1.06 (p-value <0.001). CONCLUSION: clinical improvement of symptoms and the patient profile followed the worldwide trend, with emphasis on the etiology secondary to Chagas disease, endemic in Brazil. Gastroesophageal reflux remains the main post-operative symptom.
format Online
Article
Text
id pubmed-10578864
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Colégio Brasileiro de Cirurgiões
record_format MEDLINE/PubMed
spelling pubmed-105788642023-10-17 Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term FRANÇA, IGOR RABELO DE CALDAS, EDUARDA AUGUSTA DE LUCENA BARROS, MARCELLA FERREIRA SILVA, JOSE TARCÍSIO DIAS DA PONTUAL, JOÃO PAULO FERRAZ, ÁLVARO A. B. Rev Col Bras Cir Original Article INTRODUCTION: achalasia is a chronic disease. Since there is no curative treatment, diagnosed patients have pharmacological and/or surgical techniques available, aimed at minimizing the condition. POEM appears as a promising new type of palliative treatment with good rates of symptom improvement. OBJECTIVE: evaluate the profile of POEM at the Clinical Hospital of the Federal University of Pernambuco (HC - UFPE) and correlate it with the world scenario. METHODS: data collection was performed retrospectively from September 2017 to October 2019 with all patients undergoing POEM at the HC - UFPE. Sociodemographic, clinical, and hospital variables were evaluated before and three months after the procedure. RESULTS: of 27 patients (52.41 ± 19.24 years old) who underwent the procedure, 66.7% had idiopathic etiology and 33.3% had etiology secondary to Chagas disease. 48% patients underwent previous procedures, of which seven used some type of medication for symptom control, two underwent pneumatic endoscopic dilation, and four underwent Heller cardiomyotomy with partial fundoplication. 62.5% of the evaluated patients had type II achalasia before the procedure. Seven (25.9%) patients presented the following adverse events: four presented bleeding, two pneumoperitoneum, and one both complications, all being treated conservatively. The Eckardt score reduced from 8.37 ± 1.45 to 0.85 ± 1.06 (p-value <0.001). CONCLUSION: clinical improvement of symptoms and the patient profile followed the worldwide trend, with emphasis on the etiology secondary to Chagas disease, endemic in Brazil. Gastroesophageal reflux remains the main post-operative symptom. Colégio Brasileiro de Cirurgiões 2022-12-02 /pmc/articles/PMC10578864/ /pubmed/36629719 http://dx.doi.org/10.1590/0100-6991e-20223244-en Text en © 2022 Revista do Colégio Brasileiro de Cirurgiões https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
FRANÇA, IGOR RABELO DE
CALDAS, EDUARDA AUGUSTA DE LUCENA
BARROS, MARCELLA FERREIRA
SILVA, JOSE TARCÍSIO DIAS DA
PONTUAL, JOÃO PAULO
FERRAZ, ÁLVARO A. B.
Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
title Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
title_full Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
title_fullStr Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
title_full_unstemmed Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
title_short Peroral endoscopic myotomy for the treatment of achalasia in the Unified Healthcare System (SUS): results of a short-term
title_sort peroral endoscopic myotomy for the treatment of achalasia in the unified healthcare system (sus): results of a short-term
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10578864/
https://www.ncbi.nlm.nih.gov/pubmed/36629719
http://dx.doi.org/10.1590/0100-6991e-20223244-en
work_keys_str_mv AT francaigorrabelode peroralendoscopicmyotomyforthetreatmentofachalasiaintheunifiedhealthcaresystemsusresultsofashortterm
AT caldaseduardaaugustadelucena peroralendoscopicmyotomyforthetreatmentofachalasiaintheunifiedhealthcaresystemsusresultsofashortterm
AT barrosmarcellaferreira peroralendoscopicmyotomyforthetreatmentofachalasiaintheunifiedhealthcaresystemsusresultsofashortterm
AT silvajosetarcisiodiasda peroralendoscopicmyotomyforthetreatmentofachalasiaintheunifiedhealthcaresystemsusresultsofashortterm
AT pontualjoaopaulo peroralendoscopicmyotomyforthetreatmentofachalasiaintheunifiedhealthcaresystemsusresultsofashortterm
AT ferrazalvaroab peroralendoscopicmyotomyforthetreatmentofachalasiaintheunifiedhealthcaresystemsusresultsofashortterm